Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 24 for “"Exhaled breath"”.
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Exhaled breath analysis using laser absorption spectroscopy
… developing field, with many applications in breath diagnostics and therapeutic monitoring. For this thesis, laser spectroscopic techniques were employed to measure exhaled nitric oxide (NO), carbonyl sulfide (OCS) and carbon dioxide (CO2). A pulsed quantum cascade laser operating at 4.86 …
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Precision measurement of carbon isotope ratio in exhaled breath for the detection of helicobacter pylori
… normal">The utility of breath trace compounds as bio-markers for various physiological conditions has long been exploited for the diagnosis of various diseases. Urea breath tests have been adopted as the gold standard for the detection of Helicobacter pylori which is a …
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Detection of hydrogen peroxide and ethanol in exhaled breath using biosensors: Considerations in standardizing breath collection
Breath monitoring is a non-invasive, safe, and repeatable approach to determining the health status of humans and other mammals. Breath samples could be detected in two ways directly sensing exhaled breath (EB) or chilling the EB to obtaining the exhaled breath condensate (EBC). Each has its …
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Development of a sampling system for the collection of exhaled breath condensates and its subsequent analysis using 2-dimensional gas chromatography
Exhaled human breath contains thousands of compounds that provide information about the physiological state of the human body, yet it is not used as extensively as blood or urine samples for medical diagnostics. Some of the major reasons for this include the lack of a standard method of sample …
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Assessment of a methodology for determination of H[2]O[2] concentration and pH in exhaled breath condensate in horses with and without lower airway inflammation
… hydrogen peroxide (H2O2) concentration and pH in exhaled breath condensate (EBC) is useful for detection and monitoring of diseases of the lower respiratory tract in humans, including asthma and chronic obstructive pulmonary disease. In contrast, limited information on the use of these parameters …
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Capnographic analysis for disease classification
… information from carbon dioxide in the exhaled breath are qualitative, through visual inspection, and therefore imprecise. In this thesis, we quantify the CO₂ waveform, or capnogram, in order to discriminate among various lung disorders. Quantitative analyses of the capnogram are …
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Terahertz wave-molecule interactions via CMOS chips : from comb gas sensor with absolute specificity to ultra-stable, miniaturized clock
… analysis of complicated gas mixtures (e.g. human exhaled breath and industrial gas leakage). To utilize this important property, a CMOS dual-frequency-comb spectrometer is proposed and implemented. Broadband (220~320GHz), fast scanning (20x faster than conventional single-tone sensors) and highly …
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NON INVASIVE CANCER DETECTION: FROM BENCH TO BEDSIDE
… cancer markers were identified using end-tidal exhaled breath. A novel plant inspired, robust, low-cost, eco-friendly and easy to use chemiresistive volatile sensor array was developed. In future, this novel sensor array could be used as diagnostic tool for detecting cancer.
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Fluorinated Graphene Oxide Based Chemiresistive Gas Sensor Targeting NH3 and Other Analytes Under Atmospheric Conditions
… continuous health monitoring applications in exhaled breath testing.
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Development and validation of a diagnostic tool for occupational asthma based on serial lung function measurements
… than FEV1, although FEV1 was more reproducible. Exhaled breath nitric oxide (FENO) showed similar ABC scores between those with normal and raised FENO. FENO was significantly correlated to methacholine reactivity. In shift workers, mean ABC scores were increased on morning shifts compared to …
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Improving smoking cessation for vulnerable populations in low-resourced settings
… at 6 months was biochemically verified using exhaled breath carbon monoxide (CO) and urine cotinine test. Modified Poisson regression models examined the association between NMR (high vs. normal) and 6-month abstinence. Effect modification (on the additive and multiplicative scale) examined …
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Biomarkers of oxidative stress and inflammation in biological samples collected from recurrent airway obstruction (RAO)-affected horses and their controls
… inflammatory and oxidative stress biomarkers in exhaled breath condensate (EBC), bronchoalveolar lavage fluid (BALF), red blood cells, white blood cells, and plasma; and cytokine expression in airway inflammatory cells and mucosal biopsies of RAO-affected horses and their controls. Sixteen horses …
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Applications of Proton Transfer Reaction and Selected Ion Flow Tube Mass Spectrometry in Health Monitoring
… VOCs may be found in the human body, in exhaled breath, faecal matter, urine, and skin. Analysis of the volatile profile produced in the human body can provide an indicator of metabolic status, allowing the screening and monitoring of different diseases and conditions, non-invasively and …
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Characterisation of exacerbations in non-CF Bronchiectasis to establish endpoints in measuring treatment efficacy
… by a visual analogue score are useful endpoints. Breathlessness is a reliable endpoint when measured using either a visual analogue score or modified Borg’s breathlessness score. Health related quality of life measured using the Euroqol questionnaire is a sensitive marker of change during an …
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Health Assessment of Artisanal Metal Work: Injury Patterns, Aerosol Exposures, and Biomonitoring
… biological matrices: blood, urine, saliva, and exhaled breath condensate (EBC). Blood samples yielded the most consistent quantification, particularly for manganese and chromium, and correlated with personal air concentrations. Saliva and EBC also showed promise as non-invasive alternatives for …
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Exhaled nitric oxide in asthmatic airway inflammation
Measuring the level of exhaled NO (eNO) in the breath is a new method to monitor airway inflammation in asthma and may have a role in the management of asthma. The hypotheses were that eNO will reflect the degree of inflammation in chronic asthma, and will indicate how anti- inflammatory therapy …
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A fundamental study of epitaxial graphene on silicon carbide on silicon for mid-infrared nanophotonics
… exciting spectrum for many applications such as exhaled breath detection, cancerous tissue diagnosis, water quality monitoring, greenhouse gas detection, machine vision, and navigation. Plasmonics has enabled sub-diffraction confinement and manipulation of light. However, the high losses and lack …
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Automated Detection of Incomplete Exhalation as an Indirect Detection of Auto-PEEP on Mechanically Ventilated Adults
… Incomplete exhalation occurs when the exhaled breath never reaches a flow rate of 0 L/min. The objective of this dissertation is to develop an automated detection system of auto-PEEP through incomplete exhalation as revealed by ventilator graphics for mechanically ventilated adults. …
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Nitric oxide in airway inflammation
Exhaled breath condensate (EBC) is a non-invasive method of investigating airway inflammation associated with nitric oxide (NO) and the metabolites nitrite/nitrates (NOx) in diseases such as chronic obstructive pulmonary disease (COPD), but some of the variables affecting the results are unknown. …
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