Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 281 for “"Excitability"”.
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Nonlinear resonance and excitability in interconnected systems
… in the contexts of nonlinear resonance and excitability, two phenomena with the potential of encompassing a large number of applications. The first interconnection is considered in the context of vibration absorption. It corresponds to coupling two Duffing oscillators, the prototypical …
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Modulation of corticospinal excitability during arm cycling in humans
… implemented to examine supraspinal and spinal excitability, and bridge the gap between animal and human research. Therefore, this thesis set out to determine changes in corticospinal excitability in biceps brachii during different motor outputs, including those generated by spinal CPGs. The …
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Cortical Excitability after Mild Traumatic Brain Injury in Children
… but recent research suggests that cortical excitability may play a role. Objectives: To determine if cortical excitability is different in pediatric mTBI, and if it correlates with symptom persistence. Methods:This was a cross-sectional controlled cohort study. Cortical excitability was …
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Factors affecting the excitability of skinned fibres of the rat
… referred to, sometimes, as skinned fibre excitability. More specifically, the work presented in this thesis is concerned with the relationship between rat skinned fibre excitability and (i) developmental age, (ii) MHC composition, muscle of origin and (iii) glycogen content.
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Virtual reality visual feedback and its effect on brain excitability
… feedback in virtual reality (VR) to increase excitability of distinct neural networks in the sensorimotor cortex. The objective is to explore neural responses to visual feedback of motor activities performed in complex virtual environments during functional magnetic resonance imaging (fMRI), …
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Regulation of Neuronal Excitability by Glutamate and Cholecystokinin Rodent Neocortex
The excitability of neuronal networks may also be modulated by neuropeptides. Cholecystokinin (CCK) is one of many neuropeptides localized in the central nervous system with relatively high concentrations in the cerebral cortex. Layer VI neocortical neurons provide important corticothalamic …
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The Relationship between Ephaptic Coupling and Excitability in Ventricular Myocardium
Introduction: Excitability in cardiomyocytes is dependent on the subthreshold current required to raise transmembrane potential to the activation threshold and subsequent recruitment of voltage gated sodium channels to trigger an action potential. Conduction in cardiomyocytes is dependent on the …
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Ion channels and electrical excitability in native murine anterior pituitary corticotrophs
… with TRAM-34 lead to an increase in corticotroph excitability with firing pattern transition from single spikes to “pseudo plateau bursting”. When A-type potassium channels were blocked, the afterhyperpolarization amplitude of single spikes was decreased in some corticotrophs. In native murine …
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Sympathetic control of carotid body excitability in hypertension: A preclinical study
… hypertonicity and hyperreflexia (i.e., hyper-excitability), which is not fully understood. Our aim was to test whether carotid body hyper-excitability is mediated by its sympathetic innervation. Chemoreflex was activated (NaCN 50-100 μL, 0.04%) in Wistar and SH rats in situ before and after: …
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Variations of Excitability in the Central Nervous System of the Crayfish
Made available in DSpace on 2014-12-05T22:14:33Z (GMT). No. of bitstreams: 1 0009143.pdf: 6344907 bytes, checksum: f722faf0bce35d39ac001b239d13945b (MD5) Previous issue date: 1954
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The regulation of neuronal excitability by epilepsy-associated gene Nedd4-2
… suffer from an imbalance in neuronal and circuit excitability and present with seizure or epilepsy as the common comorbidity. The onset of epilepsy can be a result of an acquired brain injury (such as a trauma) or a genetic mutation in some genes. It is widely accepted that the alterations in …
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Regulation Of Neuronal Excitability: New Mechanisms For Slow Afterhyperpolarization Activation And Modulation
… a critical role in the regulation of neuronal excitability. This current is modulated by receptors acting via GΑ<sub>q/11</sub> G proteins, thus it is thought that neurotransmitters regulate neuronal excitability through the inhibition of this current. I<sub>sAHP</sub> is known to be mediated …
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The Effects of Cryotherapy on Quadriceps Corticospinal Excitability in Patients withPatellofemoral Pain
… cryotherapy can alter quadriceps corticospinal excitability in patients with patellofemoral pain. Design and Setting: A blinded, crossover study was conducted in a laboratory setting. Subjects: Eight patients (1 male, 7 females; 19.6±1.11 years; 163.37±10.27 cm; 59.53±10.11 kg) with …
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The effects of social-comparative feedback on corticospinal excitability and balance performance.
… response that subsequently, alters corticospinal excitability. This is based on studies observing correlations between valence, corticospinal excitability and balance performance. However, the neural processes contributing to the motor and cognitive benefits of social-comparative feedback have not …
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Regulation of Thalamic Neuron Excitability and Intrathalamic Rhythms by Vasoactive Intestinal Peptide
I found that VIP selectively increases the excitability of thalamic relay neurons by producing a long-lasting depolarization. These actions lead to antioscillatory actions of VIP on intrathalamic rhythmic activity (Chapter 2). The excitatory and antioscillatory actions of VIP are predominantly …
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Intrinsic Properties and Neuromodulator Regulation of Neuronal Excitability of Intralaminar Thalamic Neurons
… of neurokinins on parafascicular nucleus neurons excitability. Substance P, neurokinin A, and neurokinin B strongly depolarized the majority of neurons tested via a decreased potassium conductance. The neurokinins can alter the excitability of parafascicular nucleus neurons, and thereby have a …
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Mechanisms Underlying Mesenchymal Stem Cell-Derived Extracellular Vesicle Modulation of Sensory Neuron Excitability
… of OA by reducing OA-induced sensory neuron hyperexcitability, rather than altering joint pathology. These findings underscore the therapeutic potential of MSC-EVs in pain management. We further showed that MSC-EVs can directly inhibit sensitisation of dorsal root ganglion (DRG) neurons induced by …
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Fatty acid ethanolamides pinpoint nicotinic receptors and modulate neuronal excitability through nuclear receptor PPARα
SPECIFIC AIMS OF THE STUDY 1) To investigate whether FAEs can suppress nicotine-induced stimulation of VTA dopamine (DA) neuron firing rate through the peroxisome-proliferator-activated receptor-α (PPARα) and to elucidate their mechanism of action in an in vitro brain slice preparation. 2) To …
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Regulation of survival and synaptic connectivity in the adult brain by cell-intrinsic excitability
… in our understanding of how the cell-intrinsic excitability of new neurons governs their incorporation into mature circuits in the adult brain. Contrary to the notion that adult neurogenesis represents continual addition of the same type of neurons that are incorporated during brain development, …
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