Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"ExWAS"”.
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Detection, causes and consequences of sex chromosome mosaicism
… 5, the first exome-wide association study (ExWAS) for LOY was conducted on over 80,000 men from UK Biobank. As well as CHEK2, which had been identified on a previous GWAS on LOY, a novel gene, GIGYF1, was identified, in which loss-of-function variants increased the risk of LOY and Type 2 …
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Genomic and metabolomic interrogation of body composition and insulin resistance endotypes
… i.e. genome/exome wide association studies (GWAS/ExWAS), identify common variation shaping risk of more prevalent forms of disease. Healthy skeletal muscle and adipose tissue support physical function and cardiometabolic resilience across the life course. In the general population age-related …
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Genetic Determinants of Body Weight and Physical Maturation Across the Life Course
Evidence points to early life as a critical period of heightened susceptibility to factors that alter the risk of later-life non-communicable diseases. Two early life risk factors increasingly recognised as important for adult health are early puberty timing and childhood obesity. Both factors are …