Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 968 for “"Ex-vivo"”.
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Precision Diagnostics of Donor Lungs Ex Vivo
Ex vivo lung perfusion (EVLP) is an advanced technology that reconditions donor lungs prior to transplantation. Lung monitoring during EVLP provides isolated lung data without confounding factors from other physiological systems. Herein, we used machine learning modelling to process EVLP diagnostic …
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Optimizing Ex Vivo Culture of Satellite Cells
… (aryl hydrocarbon receptor). So, I described the expression pattern of AHR in different stages of satellite cells.
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„Ex vivo” Replikation des pathogenen Prion Proteins
… kann entweder spontan oder induziert durch exogenes PrPSc erfolgen. Dabei kommt es zur Anlagerung von PrPSc an PrPC. Diese Erkrankung wirkt sich vor allem im Gehirn der betroffenen Organismen aus. Dabei kommt es zur Ausbildung eines durchlöcherten schwammartigen Gewebes mit amyloiden …
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Ex Vivo Deformations of the Uterosacral Ligaments
… structures are over-stretched, become weak, and exhibit laxity, pelvic floor disorders such as pelvic organ prolapse occur. Although several surgical procedures to treat pelvic floor disorders are directed toward the USLs, there is still a lot that is unknown about their function. These surgeries …
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Ex Vivo Induction of Human Regulatory T Cells
… a CD14+ cell subset with increased cell surface expression of CD36 and the TGF-beta related latency associated peptide, LAP. We termed this unique cellular subset CD14+CD36HI monocytes, and further demonstrated their expression of the LAP-TGF-beta binding transmembrane molecule GARP, functioning …
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Computergesteuertes Perfusionssystem zur normothermen ex-vivo Vorbehandlung von Dünndarmtransplantaten
… liefert, stellt sich die Frage, ob eine ex-vivo Vorbehandlung des Organs zur Reduktion der Immunogenität Vorteile bietet. Für dieses Vorhaben wurde ein computergesteuertes ex-vivo Perfusionssystem entwickelt, das eine mehrstündige, normotherme Perfusion mit erythozytenhaltigen …
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Examination of ex-vivo lung perfusion in porcine model
… number of patients awaiting a lung transplant. Ex-vivo lung perfusion (EVLP) is an established technique that may potentially allow more donor lungs to be reconditioned and provide waiting list patients with a better opportunity for transplantation. During EVLP, lungs are connected to a circuit …
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Ex-vivo 3D assessment of carotid stenosis with ultrasound
… the area over which one can evaluate the extent of the disease. Reproducing the identical scan plane on subsequent scans is also difficult. Evaluation of the carotid vessel wall in 3D will allow for a more complete and reproducible assessment of disease through IMT measurements. We have …
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Ex-Vivo Injection of Biomaterial Biologics for Treatment of Osteonecrosis
… was to maximize microsphere distribution in an ex vivo humeral head osteonecrosis model. The hypothesis was that bone washing, smaller microsphere size, higher microsphere concentration, hydrogel carrier, larger inter-needle distance, and increased needle number would maximize microsphere …
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Efficient Methods for Ex Vivo Generation of Gene-edited Neutrophils
… from the circulation of healthy adults can be expanded and directed to differentiate into mature neutrophils using granulocyte colony stimulating factor, and that these cells recapitulate multiple functions of mature circulating neutrophils. Stable modification of progenitors by Cas9 …
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The Development of Ex vivo and In vivo Multiphase NMR Spectroscopy
… biological and environmental samples are complex heterogenous mixtures composed of multiple phases (solids, liquids and gels). It is the interaction between these phases that give rise to environmental reactivity and biological function in intact samples. As traditional NMR has evolved as …
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Ex-Vivo Slaughterhouse Porcine Crystalloid-Perfused Beating Heart via Langendorff Method
… buffer reperfusion instead of blood via an extracorporeal Langendorff apparatus. The isolated beating heart functions outside of the body under simulated physiologic conditions. Live functional anatomy was controlled under benchtop experimental settings. Porcine hearts (26 total) were …
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Ex vivo culture of patient tissue and examination of gene delivery
… tissue, cut into thin slices and maintained ex vivo and is universally applicable to gene delivery methods, using a real-time luminescence detection method to assess gene delivery. The nature of the ex vivo culture system permitted examination of specific physiological variables, the …
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Viral Factors Influencing Early Infection Events During Ex-Vivo KSHV Infection
… in western countries mostly affects the homosexual population, while in the malaria-belt, both men and women can be affected equally. All forms of diseases caused by KSHV are uniformly fatal highlighting the need for research into KSHV virology for the identification of possible druggable …
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Computational Models of Ex Vivo HIV-1 Dynamics and Fitness Across Scales
… when moving from one scale to another. We explore this issue in the context of growth competition assays, used to quantify the ex vivo replicative fitness of two HIV-1 isolates, by developing cell level and macroscopic models, and investigating the relationship between the model parameters …
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Vulnerability of ex vivo α-motor nerve terminals to hypoxia-reperfusion injury.
… to further characterise this vulnerability by examining the response of mouse α-motor nerve terminals at the neuromuscular junction (NMJ) to hypoxia-reperfusion injury. To address this aim, a novel model system was generated in which ex vivo skeletal muscle preparations could be maintained in …
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