Global ETD Search
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Showing 1 to 6 of 6 for “"Eukaryotic Initiation Factors"”.
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Elucidating the Roles of Eukaryotic Initiation Factors Involved in DAP5 Mediated Translation
<p>Translation initiation in eukaryotes is a highly regulated process essential for accurate protein synthesis. It is a dynamic process that involves a complex interplay between messenger RNAs (mRNAs), ribosomal subunits, and a host of initiation factors, ensuring precise start codon selection and …
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Eukaryotic Initiation Factor 3 Interactions with Structural Elements of Barley Yellow Dwarf Virus Untranslated Regions Reveal Details of a New Cap-Independent Translation Initiation Model
… 5′ and 3′ untranslated regions (UTRs) to recruit eukaryotic initiation factors (eIFs) and ribosomes. BYDV’s 3′ translation enhancer (BTE) is a cruciform structure capable of recruiting the cap-binding complex eIF4F, the large scaffolding complex eIF3, and the 40S ribosomal subunit. Together eIF3, …
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Regulation of HIF-1α during Hypoxia by DAP5-Induced Translation of PHD2
… (DAP5) is an atypical isoform of the translation initiation scaffold eukaryotic initiation factors 4GI and II (eIF4GI/II), which recruit mRNAs to ribosomes in mammals. Unlike eIF4GI/II, DAP5 binds eIF2β, a subunit of the eIF2 complex that delivers methionyl-tRNA to ribosomes. Despite extensive …
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The Role of Secondary and Tertiary Structure in the Cap-Independent Translation of FGF-9 and HIF-1-alpha
… of the 5’ cap. However, under cellular stress, eukaryotic translation must be initiated through a 4E-independent, or “cap-independent” mechanism, involving eukaryotic initiation factor 4G (eIF4G) binding directly to the 5’ untranslated regions (5’ UTR) of the RNA. eIF4G binding then recruits the …
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The role of extracellular signal-regulated kinases (ERKs) in T lymphocytes
… T cells lacking active ERK1/2 proteins included eukaryotic initiation factors, glucose and amino acid transporters, cytokines like IL-2, cytolytic molecules such as granzyme B, surface molecules such as CD25 and transcription factors like EGR1. These results provide a comprehensive understanding …
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The Effect of Post Exercise Nutrition on Anabolic Response to Resistance Exercise
Purpose: To determine the effect of four postexercise beverages, differing in macronutrient content, on metabolic response to an acute resistance exercise bout. Methods: Forty male subjects performed five sets of eight repetitions at 80% 1RM for leg press and leg extension, and then consumed one of …