Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 21 for “"Eukarya"”.
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Origin and evolution of protein fold designs
… of structural sharing between Archaea and Eukarya that are very recent. Trees of proteomes confirmed the early appearance of Archaea in the world of organisms. Phylogenies reconstructed from phylogenetic character sets representing T and H domains of different age congruently reflected …
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Origin of viruses revealed by the genomic study of protein domain structures
… cellular superkingdoms Archaea, Bacteria, and Eukarya. Universal trees of life (uToLs) place viruses at their root and trees of domains indicate they have evolved via massive reductive evolutionary processes. Since viral domains are widespread among cellular proteomes we propose that viruses …
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Prion biology in the context of bacteria
… prion-like phenomena has been confined to the Eukarya. The work presented in this thesis seeks to explore the possibility that prion-like mechanisms are operative in the bacterial domain of life. In what follows, we demonstrate that Escherichia coli cells can propagate a model yeast prion in a …
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Bridging the gap between microbial and metazoan evolutionary history
… from Bacteria into Metazoa, Opisthokonta, and Eukarya, and use two of them to constrain the ages of the bacterial phylum Bacteroidetes and the archaeal family Methanosarcinaceae.
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Structural and functional advances in the evolutionary studies of cells and viruses
… early origin of Archaea relative to Bacteria and Eukarya, a conclusion further supported by comparative analysis. The analysis further revealed an ancient history of viruses and their evolution by gene loss. Despite the very high levels of variability seen in the replication strategies, …
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Approaching the Three-Dimensional Organization of the Human Genome
… of completely sequenced Archaea, Bacteria and Eukarya chromosomes revealed fine-structured positive long-range correlations due to codon, nucleosomal or block organization of the genomes, allowing classification and tree construction. By construction and expression of fusionproteins from the …
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Investigating a novel Asgard archaeon and its tubulin-like proteins
… a strong affiliation between Asgard Archaea and Eukarya, either as sister lineages or with Eukarya emerging from within the Asgard Archaea phylum, making these Archaea essential for studying the origin of eukaryotes. Moreover, the cytoskeleton is a vital, dynamic network of proteins that …
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New Sensing Modalities for Bacterial and Environmental Phenomena
… of life, ranging from archaea to bacteria to eukarya. In bacteria, this is often achieved using small molecules that allow bacteria to sense and respond to environmental cues about the presence, identity, and number of neighboring bacteria. This confers survival and competitive advantages to …
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A preliminary analysis of the lipid contents of a biofilm from a Yellowstone hydrothermal pool
… pool. Some compounds that were indicative of eukarya were also identified, although a more in-depth study is necessary to determine whether these signals were from the pool or from external inputs. The lipids identified in this study indicate that the genomic diversity established by previous …
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Eukaryotic Microbes in the Deep Sea: Abundance, Diversity, and the Effect of Pressure
… defined as the microbial portion of the domain Eukarya, are particularly neglected in studies of deep-sea microbiology. Here, I present three studies on microbial eukaryotes in the deep sea: first, a study of the abundance of microbial eukaryotes in the deep sea, second, a quantitative approach …
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Functional Analysis of Novel Replication Protein a Homologs in the Euryarchaeota: Implications in the Evolution of Single -Stranded DNA Binding Proteins Across the Three Domains of Life
… In the Archaea, which together with Bacteria and Eukarya constitute the three domains of life, single-stranded DNA binding proteins have been described for only thermophilic and hyperthermophilic organisms, although this domain includes numerous mesophilic genera. As observed with other proteins …
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Comparative genomic approaches for investigating evolution in the microbial and viral populations of the rumen
… three domains of life: Bacteria, Archaea, and Eukarya. Viruses have also been documented to be present in large numbers; however, little is currently known about their role in the dynamics of the rumen ecosystem. This research aimed to use a comparative genomics approach in order to assess the …
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Structure Function Analysis of Adenosine Deaminase Acting on tRNA (ADAT2) from Trypanosoma Brucei
… (ADAT) and modifies only tRNAarg, whereas in eukarya the enzyme is the ADAT2/3 heterodimer, which performs the same reaction on all tRNA molecules with adenosine at position 34. Despite a similar evolutionary origin, the characteristics of these two enzymes are significantly different. …
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Metagenomic Analyses of the Human Gut Virome
… three domains of life, Bacteria, Archaea, and Eukarya; most are members of Bacteria. These organisms collaborate and compete for functional niches and physical space: habitats), together forming a continuously functioning metabolic organ that influences many aspects of host biology. The factors …
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STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF ARCHAEAL BOX H/ACA RIBONUCLEOPROTEIN INVOLVED IN RIBOSOMAL RNA PSEUDOURIDYLATION
… is pseudouridine (Y) formation. In Archaea and Eukarya, pseudouridine synthases, with the help of small RNAs, form pseudouridines at functionally important regions in rRNA. Cbf5, the pseudouridine synthase, three other core proteins, and a box H/ACA RNA form the ribonucleoprotein complex in …
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Methodological advances for the measurement of the D-amino acids across the metazoa: From mollusks to man
… in every domain of life (Archaea, Bacteria and Eukarya). Beyond their ubiquitous presence, a few D-amino acids have been demonstrated to act as cell-to-cell transmitters and functional roles in the central nervous and endocrine systems have been uncovered. In spite of great progress made in our …
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STRUCTURAL AND FUNCTIONAL STUDIES OF ARCHAEAL BOX C/D GUIDE RNA AND ROLE OF A PUTATIVE HUMAN PSEUDOURIDINE SYNTHASE, PUS10 IN APOPTOSIS
… target RNA for modification. Both in Archaea and Eukarya, box C and box D, as well as box C’ and box D’ together can form a structure called a Kink-turn (K-turn) that is characterized by a canonical Watson-Crick base-paired stem on one side, and a non-canonical stem on the other, separated by a …
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Biochemical and structural characterization of radical SAM enzymes Elp3 and viperin
… Neither cm5U nor mcm5U/ncm5U (modification in eukarya) was detected in the archaea; however, two new substances (549 Da and 454 Da) were detected. Further analysis is required to determine if these substances are the result of a secondary reaction on cm5U. The SAM domain of Elp3 contains the …
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Protein O-Kinases in the Archaeon Sulfolobus solfataricus
… known to occur in all three domains of life <i>Eukarya, Bacteria,</i> and Archaea</i>. Very little is known, however, concerning the origins and evolution of protein phosphorylation-dephosphorylation. Knowledge of the structure and properties of the protein kinases resident in the members of the …
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Exploring early-life microbiome transfer and therapeutic applications in bovines and humans
… communities, including bacteria, archaea, eukarya, viruses, bacteriophages, and their associated products. These dynamic entities establish symbiotic relationships with their bovine and human hosts, exerting direct or indirect influences on physiology throughout life, impacting both health …
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