Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Ets-1"”.
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MicroRNA as Regulator of the Th17 Inflammation in Behcet's disease
… blotting were carried out to determine whether Ets-1 is a target of miR-155. Subsequently, Ets-1 expression was quantified using real-time PCR in patients and controls. Western blotting was also performed to investigate the relationship between Ets-1 and IL-17 in patients with active BD and …
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Interaktionen von humanen mesenchymalen Stromazellen (hMSC) mit Plattenepithelkarzinomzellen des Oropharynx in indirekter Kokultur
… β-Catenin, MMP-14, E-Cadherin, Cathepsin B und Ets-1 bei den Tumorzellen. Unsere Ergebnisse zeigen, dass sich Proliferation und Genexpression von PCI-13-Zellen in Kokultur von den jeweiligen Einzelkulturen signifikant unterscheiden. Nach 7 Tagen zeigt sich bei den Tumorzellen sowohl für Wnt-3 …
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Identifizierung und Charakterisierung von Genen für die Entwicklung des cerebralen Cortex
… und für die Transkriptionsfaktoren Ets-1 und Pax6 identifiziert. In der vorliegenden Arbeit wurde eine verringerte Expression von PIPPin in der homozygoten Pax6-Mutante "Sey" beobachtet. Weiterführende Deletionsanalysen des PIPPin-Enhancers werden zeigen, inwiefern ein direkter …
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Mcam/Muc18 Regulates Melanoma Progression By Modulating The Expression of Id-1
… at the transcriptional level through Sp1 and Ets-1. This is the first report to demonstrate that MUC18 does not act exclusively in cell adherence, but is also involved in cell signaling that regulates the expression of genes, such as Id-1 and ATF-3, thus contributing to the metastatic melanoma …
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Molecular Basis of Upregulation of IL-17 in Estrogen Model of Inflammation
… and/or expression of negative regulators (IRF8, ETS-1). In addition, we found that estrogen epigenetically regulates IL-17 induction by miRNAs (miR-326 and miR-223). We also found that majority of IL-17 positive cells are CD8⁺ suggesting that estrogen-mediated IL-17 induction is predominantly …
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The Influence of a Single Nucleotide Polymorphism In The Matrix Metalloproteinase-1 Promoter on Glioma Biology
… guanine nucleotide creates a binding site for ETS transcription factors and combined with the AP-1 binding site at position -1602 creates a Ras Responsive Element. We determined that the distribution of the MMP-1 genotype differed significantly between the healthy population and the …
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SF-1, BUT NOT DAX-1, PREVENTS P19 CELLS FROM DIFFERENTIATING TO EITHER TROMA-1 OR TUJ1 POSITIVE CELLS UPON RA-TREATMENT
… and the increase in COUP-TFI, COUP-TFII, and Ets-1 mRNA levels during the commitment stages of both endodermal and neuronal differentiation. Surprisingly, continued expression of SF-1 for seven days caused a RA-independent loss of Oct-4 protein. However, cells which continued to express SF-1 …
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Pathogenic and Protective Potential of B Cell Dysregulation in Systemic Lupus Erythematosus
… between the src tyrosine kinase, Lyn, and the Ets family transcription factor, Ets1, in autoimmunity. Lyn is both a positive and negative regulator of BCR signaling; however its net effect is inhibitory. Lyn deficiency results in hyperactive B cells and Lyn-/- mice serve as a murine model of …