Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"Estrogenicity"”.
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SYNTHESES AND ESTROGENICITY STUDY OF DIETHYLSTILBESTROL AND BISPHENOL-A ANALOGS AS POTENTIAL REPLACEMENT FOR BISPHENOL-A AND INVESTIGATION ON NOVEL REACTIONS INDUCED BY IODANE/QUATERNARY AMMONIUM HALIDES
… of Z-DES, were synthesized and tested for their estrogenicity. The estrogenicity of 13 is higher than that of 14 and 15, which indicates that E-DES is more estrogenic than Z-DES. Dimethylstilbestrol (16), another analog of DES, was also synthesized and tested. Its estrogenicity is lower than that …
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Assessment of the Efficacy of a Constructed Wetland to Reduce or Remove Wastewater Effluent Estrogenicity and Toxicity Using Biomarkers in Male Fathead Minnows (Pimephales Promelas Rafinesque, 1820)
… in Pimephales promelas was used to assess estrogenicity of a local municipal effluent. Vitellogenin induction in male P. promelas increased in frequency and magnitude with increased exposure duration and was greater ("=0.05) than controls after 2 and 3 weeks of exposure. The level of …
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Estrogenic and androgenic endocrine disrupting activity and risk assessment of phytoestrogens in Kenyan soya-based weaning flours
… Safety (HBMOS) method was used to estimate the estrogenicity due to daidzein and genistein in the flours.<br/><br/>Standard curves of 17(3-estradiol and testosterone hormones and some PEs in the MMV-Luc and in TARM-Luc cell lines respectively were established. PEs and flour/gruel extracts …
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Evaluation of Metabolic Endpoints for Use as Biomarkers of Exposure to Environmental Estrogens and in Bioassays of Their Activity
… C3 can serve as sensitive indicators of estrogenicity. Additionally, angiotensinogen has the potential to be a biomarker of exposure to estrogenic compounds because its measurement only requires a blood sample, while providing a sensitive biochemical endpoint to supplement the …
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IMPACT OF CONVENTIONAL AND PRECISION CATTLE MANURE APPLICATION METHODS ON HORMONE CONCENTRATIONS AND ACTIVITIES IN SURFACE WATER AND SOIL
… activity and (anti-)estrogenicity. Fresh and pen materials both contained androgenic/glucocorticoid activity, and (anti-)estrogenicity. In contrast, windrow manure samples (collected in 2019, and 2021) were mostly estrogenic and lacked androgenic/glucocorticoid …
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Estradiol and chlordecone interactions with the estrogen receptor
… the apparent tissue differences in chlordecone's estrogenicity.
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HORMONE EPIMERS REGULATE ER STRESS AND CORE REGULATORY GENES: NETWORK ANALYSIS WITH APPLICATIONS TO GLIOMA AND CHRONIC PRESSURE ULCERS
… and determine the relative androgenicity, estrogenicity and glucocorticoid activity. The results show that, at the receptor level, these androstene hormones are weak AR and even weaker ER activators. Direct androstene hormone activation of the human AR, ERα, and ERβ may not be essential for …
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Ecotoxicological Investigations in Effluent-Dominated Stream Mesocosms
… when effluents are fractionated or screened for estrogenicity. A subsequent 90-day cadmium study was initiated to assess long-term effluent and cadmium effects on fish endocrine function. Juvenile fathead minnows were placed in UNTSRF pool sections of replicate streams treated with 0, 5, 20 or 80 …
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Synthesis and structure-activity studies of skeletally modified estradiol analogues
… inversion at C-8, C-9 or C-13 upon the high oral estrogenicity associated with introduction of a 14, 17-ethano bridge into the estradiol skeleton. 3-Methoxyestra-1,3,5(10)-trien-17-one was converted conventionally into the 13α-isomer, which underwent sequential silyl enol ether formation and …
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Zebrafish as a Model for Studying Estrogen Signaling and Estrogenic Endocrine Disruption
… to be an effective new biomarker for assessing estrogenicity of chemicals. Third, high throughput screening of ToxCastTM Phase I pesticides library and NIH Clinical Collection drug library was performed using Tg(5xERE:GFP) reporter fish. A total of 26 environmental estrogens and 62 clinical …
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Sorption, degradation and transport of estrogens and estrogen sulphates in agricultural soils
… ER-CALUX® analysis revealed the formation of estrogenicity during E2-3S degradation, which could partly be explained by the formation of the metabolites E2 and E1. Transport studies with E1-3S and E1 showed that the transport and retention of both compounds were significantly influenced by the …
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Removal of Estrogens at Full and Pilot Scale Livestock Manure Treatment Systems
… to the influent; the ratio of E2 to total estrogenicity (E2-eq) averaged 76%. In the Anaerobic Digester, 38% of E2 (592 vs. 954 μg/cow/day) and 30% of E3 (338 vs. 483 μg/cow/day) mass were removed; E2 contributed more to E2-eq in the influent than in the effluent (43 vs. 26%). There was …
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Degradation and transport of veterinary antibiotics and estrogens in a vegetated buffer strip system
… overall persistence, leading to more sustained estrogenicity and greater environmental risk associated with land application of these two estrogenic compounds. Results from the VBS runoff experiment showed that the VBS buffer width impacted VA loads much more than vegetation treatment. The VBS …