Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 107 for “"Estrogenic"”.
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Estrogenic Effects of Genistein in Ovariectomized Gilts
Genistein, has a range of estrogenic actions, however only limited research has been done to investigate its effects in swine. The objective was to characterize the effects of administration of a graded dose of genistein on tissues known to be estrogen sensitive. Thirty-four post-pubertal gilts …
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Passive in-situ estrogenic potency sampling with DGT-YES
… assay, was deployed to quantify the total estrogenic potency of the compounds adsorbed to the DGT matrix. The unique dimension of this research was to extend the application of DGTs to estrogen sampling and to combine the DGT and YES technique to provide in situ quantification of the …
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Safe formulations of polyethylene and polypropylene: Exploring non-estrogenic antioxidants
Estrogenic chemicals originating in plastics materials are known to play a causative role in many health problems we face such as cancer, infertility, precocious puberty, and obesity. They have been linked to diabetes, asthma, neurological misdevelopment and increased aggression. The estrogenic …
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Estrogenic and Antiestrogenic Regulation of Cell Proliferation and Tissue Growth
Estrogenic and antiestrogenic responses were investigated in human breast cancer cells and in the rat uterus. I studied the regulation of ornithine decarboxylase (ODC) activity and polyamine concentrations by E2 and antiestrogens (AE) as an aid to understanding the dissimilar effects of E2 and AE …
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Estrogenic modulation of excitatory synaptic transmission at hippocampal temporoammonic-CA1 synapses
The hormone estrogen is believed to be an important modulator of hippocampal synaptic plasticity and function. The actions of estrogen at hippocampal Schaffer-collateral (SC)-CA1 synapses has been described in detail and at these synapses, estrogen can rapidly potentiate excitatory synaptic …
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Estrogenic Activity of the Polybrominated Diphenyl Ether Flame Retardant Mixture DE-71
… mixture DE-71 and its in vivo metabolites for estrogenic activity. MCF-7 breast cancer cells culture, ERE-luciferase gene expression, 3H-β-estradiol displacement from recombinant ERα, and ovariectomized (OVX) mice served as bioassays. Although DE-71 did not bind ERα, it was able to increase …
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Zebrafish as a Model for Studying Estrogen Signaling and Estrogenic Endocrine Disruption
… range of chemicals, which are classified as estrogenic endocrine disruptors (EEDs), can bind to ERs or GPERs, thereby interfering with estrogen signaling and causing adverse effects. Zebrafish embryos/larvae are an emerging model used in xenoestrogen studies. However, endogenous estrogen …
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Estrogenic modulation of place and response learning via specific receptor-mediated mechanisms
… important to characterize the role of each ER in estrogenic cognitive shifts. The present work examines the contributions of ER subtypes to shifts in learning and memory in ovariectomized female rats. Endogenous estrogen levels were eliminated through the surgical removal of ovaries in young adult …
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THE EFFECTS OF ESTROGENIC COMPOUNDS ON ADIPOGENESIS VIA PPARγ AND CANONICAL WNT SIGNALING
… to test the effects of synthetic and natural estrogenic compounds (BDDA, daidzein, and genistein) for their effects on the induction of adipogenic signaling, which may potentially improve WAT morphology by reducing adipocyte hypertrophy.
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The anti-estrogenic and liver metabolic effects of DHAA in rainbow trout (oncorhynchus mykiss)
… present in pulp and paper mills, may have anti-estrogenic effects in fish. A chronic-exposure toxicity experiment using immature rainbow trout (Oncorhynchus mykiss) was conducted in order to assess the endocrine disrupting and liver metabolic effects of the wood extractives DHAA and β- …
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Role of Estrogenic Biomarkers in the Prediction of Disease Risk/Survival in Postmenopausal Women
… from population-based studies indicate that estrogenic factors have a role to play in diseases affecting postmenopausal women. However studies investigating the role of estrogenic biomarkers in association to these diseases is lacking, especially in Asians. Using the Singapore Chinese Health …
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The synthesis and evaluation of estrogenic probes for in vitro and in vivo studies
… focuses on the preparation and evaluation of estrogenic probes for two types of analyses to achieve this goal: in vitro studies and in vivo studies.
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Investigations into the role of exogenous estrogenic endocrine disrupting chemicals on immune dysregulation in autoimmune disease
Estrogenic endocrine disrupting chemicals (EEDCs) are defined as chemicals that bind to estrogen receptors (ERs) and augment estrogenic functions, either through promoting or blocking estrogen receptor signaling. Recent reports highlight the growing concern surrounding environmental exposure to …
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Estrogenic and androgenic endocrine disrupting activity and risk assessment of phytoestrogens in Kenyan soya-based weaning flours
… weaning gruels is widespread in Kenya. Estrogenic and androgenic reporter gene assays (using MMV-Luc and TARM-Luc cell lines respectively) were used to characterise the transcription activity of ten PEs (apigenin, daidzein, daidzin, genistein, genistin, enterodiol, equol, formononetin, …
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Rna Polymerase Activity in the Uterus: Its Kinetic Properties and the Effects of Estrogenic Hormones on Its Activity
Made available in DSpace on 2015-05-14T14:57:13Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 7514154.PDF: 4759696 bytes, checksum: 885f07eb3f74794b1ae4d4056252c7f5 (MD5) Previous issue date: 1975
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Conjugated Estrogen Receptor Probes: An Evaluation of Fluorophores, Photolabile Groups, Estrogenic Ligands, and the Nature of the Attaching Chain
A good correlation exists between the level of estrogen receptor in breast tumors, and their responsiveness to hormone therapy. However, the correlation is not perfect; about 40% of women with measurable tumor receptor levels do not respond to hormone treatment. The work described herein was …
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Factors affecting estrogen excretion in dairy heifers
… The objective of the first study was to quantify estrogenic activity in feces and urine during the estrous cycle. Ten non-pregnant Holstein heifers were fed the same diet for 28 d. Plasma, feces, and urine samples were collected daily. Plasma 17-β estradiol (17-β E2) was quantified with RIA and …
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Biochemical and Biophysical Studies on the Human Estrogen Receptor and Receptor Co -Regulator Interactions
… of the tissue selective pharmacology seen with estrogenic and anti-estrogenic compounds.
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A study on endocrine disrupters in the environment through the microarray technology
… is becoming increasingly relevant. The estrogenic activity of various compounds, described as xenoestrogens, is the major part of this debate. Humans beings are exposed to these substances from different environmental contaminations ranging from conscious intake of estrogenic substances, …
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