Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Estrogen receptor subtypes"”.
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I. Design and synthesis of estrogen receptor gene switches. II. Design and synthesis of estrogen receptor ligands occupying an auxiliary binding pocket
The estrogen receptor (ER) is ligand-regulated nuclear hormone receptor and an important therapeutic target for breast cancer, hormone replacement therapy, contraception, and osteoporosis. Novel organic cores have been identified and developed as possible estrogen pharmaceuticals. The x-ray …
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The Identification and Characterization of Estrogen Receptors in the Mouse and Human Lens and Their Role in Cataract Development
… women and studies in animal models suggest that estrogen may have a protective role in the lens. However, very little is known regarding the role of estrogen and its receptors in the lens. To begin unraveling the estrogen signaling mechanism in the lens, the following aims were investigated: 1) …
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Analyse molekularer Mechanismen der ERα- und ERβ-vermittelten Wirkung spezifischer Liganden und des Phytoestrogens Genistein
… ovarektomierten Ratte die mögliche Bedeutung von estrogenrezeptorsubtypspezifischen Einflüssen für hormonell bedingte Erkrankungen und Beschwerden zu untersuchen. Hierbei sollten gewebespezifische Wirkungen estrogenrezeptorsubtypspezifischer Liganden untersucht und explizit die Bedeutung der …