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Showing 1 to 5 of 5 for “"Erythrozyt"”.
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Untersuchungen zur Gefriertrocknung biologischer Zellen am Beispiel menschlicher Erythrozyten
Freeze-drying is a state of the art process for stabilization of pharmaceutical or biotechnological products. However, a successful preservation of living cells by freeze-drying is still a big challenge. This is mainly due to increased requirements on the product quality, since even smallest …
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Mechanismen des vermittelten und nicht-vermittelten Transportes einer amphiphilen Phosphonat-Sonde (NDP2) in der Erythrozytenmembran
This dissertation concerns itself with the transversal (re-)orientation of the long-chained anionic amphiphile NDP2 [10-(Naphth-1yl)-1-decane phosphonic acid]as a probe within the two leaves of the erythrocyte membrane. The overwhelming – mediated – part of this translocation takes place via the …
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Evaluation eines Hemoresistometers
The development of blood pumps for use in heart surgery has to fulfill different demands. On the one hand there is technical performance, on the other hand there is low rate of complications. The technical performance can be tested without difficulty by in-vitro tests. Estimation of mean …
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Relevanz der enzymatischen NO-Synthese im Erythrozyten: Protektion gegen reaktive Sauerstoffspezies
The red blood cell nitric oxide synthase (RBC-NOS) is against general belief not only an inactive enzyme but produces NO• through the conversion of L-arginine to L-citrulline which is involved in the regulation of platelet aggregation. The RBC-NOS therefore represents an intracellular source for …
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Aktivität und Bedeutung der erythrozytären NOS bei kardiovaskulären Risikofaktoren
In cardiovascular diseases changes in the metabolism of L-arginine-NO cause endothelial dysfunction with reduced bioavailability of NO. Besides endothelial cells, RBC also obtain an active NOS in the vascular system. NO synthesis by RBC-NOS is regulated by similar mechanism and modulates RBC …