Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Erythrocyte invasion"”.
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The impact of common and rare human genetic variants on erythrocyte invasion by Plasmodium falciparum malaria parasites
… P. falciparum uses multiple RBC receptors for invasion, but whether DARC is one of these receptors has never been systematically explored. In contrast to Duffy negativity, the GYPA/B/E DEL1 variant results in a 110kb deletion that affects the coding regions of the GYPB gene but could also …
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Expression & Purification of Recombinant Plasmodium falciparum Erythrocyte-binding Ligands
… capable of invading all known human blood types. Erythrocyte invasion depends on specific parasite ligand and erythrocyte receptor interactions. These interactions are mediated by Region II of the P. falciparum erythrocyte binding ligands. Although invasion does not seem dependent upon a singular …
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Static and Microfluidic Live Imaging Studies of Plasmodium falciparum Invasion Phenotypes
… within it by clonal division. Merozoite invasion is a complex process involving dynamic interactions between ligands in the merozoite coat and receptors on the red blood cell membrane. Therefore, filming the complete malaria invasion processes may shed the light on its mechanism. The …
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Characterisation of the pre-invasion glycophosphatidylinositol-anchored surface proteins of Plasmodium falciparum merozoites
… from mature schizonts to invade new uninfected erythrocytes. Glycophosphatidylinositol (GPI) -anchored proteins cover most of the exterior surface of the merozoite prior to invasion, while other GPI-anchored proteins are released onto the merozoite surface through apical organelle secretions. …
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Gene expression profiling of polyamine-depleted Plasmodium falciparum
… found to be involved in cell-cell adhesion and erythrocyte invasion, protein processing and transport indicating that these processes are dependent on polyamines. Further validation of these findings by microarray as well as proteomic analysis will need to be undertaken. These results validate …