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Showing 1 to 15 of 15 for “"Ergot alkaloids"”.
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A comparison of some of the ergot alkaloids
The ergot alkaloids, other than those that are molecular compounds, fail into two groups, a laevorotatory physiologically active group, and a dextrorotatory group which is considerably less active. Smith and Timmis drew attention to this fact in their paper on isoergine and isolysergic acids (1).
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The synthesis of 4-substituted indoles and their elaboration to the ergot alkaloids
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1981.
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Nature's approach toward ring formation and structural diversity in ergot alkaloid biosynthesis
Ergot alkaloids are fungal-derived secondary metabolites well known for a diverse array of pharmacological effects both beneficial and detrimental to human health. Historically, the ergot alkaloids have been known to cause ergotism in populations that consume grain contaminated by ergot alkaloid …
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Investigations into the molecular interactions between Claviceps purpurea, the causal agent of ergot, and cereal hosts
… flowers of cereals and grasses, producing an ergot sclerotia (the overwintering structure of the pathogen) in place of a grain. C. purpurea can infect wheat, barley, rye, oats, triticale and millet, detrimentally affecting grain production and flour quality. Ergot also impacts human health …
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Consumption of Endophyte Infected Fescue During Gestation in Beef Cows
… affects cattle production. Cows consuming the ergot alkaloids produced by these endophytes can exhibit decreased feed intake, growth performance, organ vasoconstriction, and increased rectal temperature. This work is interested in examining how endophyte toxin exposure impacts pregnancy in …
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Impact of shade on cool-season forage mixtures for the Mid-Atlantic region
… U.S., harbors an endophyte that produces toxic ergot alkaloids. Diluting the sward with other forages can reduce ergot alkaloid concentrations, but it is unknown how shade impacts alkaloid production and productivity of different forage mixtures. This study tested the effects of increasing shade …
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Nutritional strategies for growing cattle in the Southeastern United States
… as well as to investigate methods of reducing ergot alkaloid intake. Corn gluten feed (CGF) is a common corn co-product that is used to supply supplemental energy and protein. Experiment 1 investigated the effect of supplementing CGF or corn to grazing cattle and found that in grazing …
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Influence of forage characteristics on grazing behavior of weaned steers
… and grazing pressure. The production of toxic ergot alkaloids by the endophyte is associated with decreased performance of animals that graze endophyte infected tall fescue. The objective of the current experiment was to determine how tall fescue type (endophyte free vs novel endophyte) and …
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Toward catalytic antibodies capable of ergopeptine hydrolysis
… environment for binding. An investigation of the ergot alkaloids produced by one grass-endophyte association (Acnatherum inebrians) known to contain high levels of ergot alkaloid was conducted. Extraction methodology and reverse phase HPLC separation systems were developed for these compounds. Use …
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The effects of extended-release eprinomectin on heifer performance and fescue toxicity and an evaluation of parasite resistance
… d 55 and 83. Serum prolactin and total urinary ergot alkaloids were similar between treatments. In addition, ERE cattle tended to have greater total CYP3A4 activity. Liver enzymes including alkaline phosphatase and gamma-glutamyl transferase were greater in ERE heifers and total protein tended …
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The Effect of Three Fescue Types and Lakota Prairie Grass on Copper Status, Dry Matter Intake, and Alkaloid Appearance of Beef Steers
… endophyte-free Kentucky 31 tall fescue (E-), non-ergot alkaloid-producing endophyte Q4508-AR542 tall fescue (Q)], and Lakota prairie grass (L; Bromus catharticus Vahl.) on animal response, alkaloid appearance, DMI, and copper status. Ergovaline (EV) is the most abundant ergot alkaloid in tall …
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Using Data Analytics in Agriculture to Make Better Management Decisions
… up close to 80% of the effect of measured total ergot alkaloids and cattle average daily gain decreased 33 g/d for each 100ppb increase in ergovaline concentration. By comparing decreased weight gain to the costs of reseeding a pasture, producers can make decisions related to the management of …
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Microbiome Metabolism in the Rumen of Bovine Grazing Toxic Tall Fescue and in Stored Dairy Manure
… species potentially capable of degrading ergot alkaloids for better feed utilization. We found that KY-31 grazing remodeled the rumen microbiome substantially at the cellulolytic and saccharolytic guilds. It suppressed the abundances of Fibrobacter, a major ruminal cellulolytic bacterium, …
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Induction of anti-ergotamine antibodies in mice and steers and protection against fescue toxicosis in mice
… and Gams) The fungus produces ergo peptide alkaloids, especially ergovaline. Consumption of endophyte-infected (ED fescue forage by cattle decreases serum prolactin and average daily weight gains, which results in economic losses for producers. Anecdotal reports suggest cattle with fescue …
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Physiological and immune responses to endophyte-infected tall fescue exposure in beef heifers: impacts on performance, metabolism, and immune cell transcriptomics
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2027-08-01