Global ETD Search
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Showing 1 to 2 of 2 for “"ErbB Receptor Family"”.
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Spatial Stochastic Modeling of the ErbB Receptor Family
ErbB transmembrane receptors are a family of 4 receptor tyrosine kinases that interact with one another through homo and heterodimer interactions. When these dimers form, the kinase domains on the receptor tails interact with one another, transphosphorylating one another, initiating a signal …
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Flourescent Biosensor-Based, Cdc42 Activity Imaging For Understanding the Regulation of Epidermal Growth Receptor (EGFR) Signalling in Head and Neck Cancer
The Epidermal Growth Factor Receptor (EGFR) is overexpressed in several solid tumours including squamous cell carcinoma of the head & neck (SCCHN). Drugs that directly block the action of EGFR are currently available. However, a major unanswered question is; how best to select patients most likely …