Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"ErSO"”.
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Improving cancer therapy strategies via cellular stress and immune modulation
… of this work focuses on the small molecule ErSO, which induces cell death through hyperactivation of the unfolded protein response (UPR). Preclinical studies in osteosarcoma (OS), chondrosarcoma (CS), and Ewing sarcoma (ES) demonstrated potent ErSO mediated cytotoxicity and anti-metastatic …
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Translational development and mechanistic insights into 3-(4- hydroxyphenyl)indoline-2-ones as a potent class of breast cancer therapeutics
… of several promising small molecules including ErSO-DFP and ErSO-TFPy. The lipophilicity and stability of these compounds appear to be key parameters determinant of antiproliferative activity and selectivity between cancer cell lines. Importantly, these derivatives are well tolerated across …
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Small molecule leveraging of the anticipatory unfolded protein response to induce marked regression in multiple human cancers
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-08-01
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Estrogen-receptor-alpha-positive breast and ovarian cancer: Therapy and mechanisms
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2025-03-28 without embargo terms