Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"Epithelial Transport"”.
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Sequence-Specific Gene Correction of Cystic Fibrosis Airway Basal Cells
… a protein involved in regulating anion trans-epithelial transport. A three-base deletion in <em>CFTR </em>(termed as ΔF508 mutation), wherein CFTR protein is misfolded leading to its pre-mature degradation in the endoplasmic reticulum (ER), is the most common cause of this debilitating …
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A pharmacological study of signal transduction mechanisms controlling fluid reabsorption and Ion transport in the locust rectum
… hemolymph composition primarily by controlling epithelial transport in the excretory system. The locust excretory system is typical of many insects and consists of the Malpighian tubules and the hindgut. The Malpighian tubules secrete a primary isosmotic urine rich in KC1 and low in Na+ that …
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NOGGIN Transport in a Model Human Epiblast
… epithelium, which points to mechanisms of trans-epithelial transport. And finally, I trace the transcytosis route of apical NOGGIN through the endosomal system. Overall, I highlight a complex mechanism where apically-secreted NOGGIN diffuses over long distance in the apical compartment; NOGGIN is …
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IN VITRO LUNG EPITHELIAL CELL TRANSPORT AND ANTI-INFLAMMATORY ACTIVITY FOR LIPOSOMAL CIPROFLOXACIN
… that Lipo-CPFX enables slower and sustained lung epithelial transport and uptake, compared to CPFX, thereby producing prolonged local pharmacological actions. The human bronchial epithelial Calu-3 cells were used as monolayers to characterize the kinetics and mechanism of transport and/or uptake, …
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Effects of agro-industrial by-products on health and growth performance of livestock: Studies on white grape marc extract in broilers and three different fibrous by-products in weaned piglets
… high GME groups, suggesting subtle effects on epithelial transport. Overall, GME exerted no adverse effects at any tested inclusion level. The second study evaluated the nutritional and physiological impact of including three fibrous by-products (carrot pomace, brewers’ spent grain, and carob …
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Anthocyanins and proanthocyanidins from blueberry and blackberry fermented beverages to reduce inflammation and type-2 diabetes: a comprehensive in vitro and in vivo evaluation
… by 233 and 100 µIU insulin/mL directly and after epithelial transport, respectively, due to reduced DPP-IV expression and up-regulated insulin-receptor associated genes and proteins (Chapter 9). Lastly, in Chapter 10 we established the role of phenolic compounds in 30:70% blueberry-blackberry …
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Apolipoprotein biosynthesis and turnover in mammalian small intestine
… and cholesteryl esters. Since the trans-epithelial transport of most of these latter materials requires the elaboration of particles partially covered by apolipoproteins, the regulation of the biosynthesis or, more correctly, the availability of these proteins is an important and as yet …
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Charakterisierung von Transportmechanismen in der Speicheldrüse der Schabe Periplaneta americana
… bzw. Speichel-modifikation beteiligten Transportmechanismen sind weitgehend unbekannt. Mikrofluorometrische Ca<sup>2+-, Na<sup>+- und pH-Messungen in Kombination mit pharmakologischen Experimenten, biochemische Messungen der Aktivitäten von Ionentransport-ATPasen sowie …
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Der Mineralokortikoidrezeptor ist keine Voraussetzung für die Stimulation des epithelialen Na+-Transportes durch Glukokortikoide-Messungen an der Mineralokortikoidrezeptor Knock-out Maus
… Arbeit befaßt sich mit der Regulation des epithelialen Na+-Transportes durch Mineralokortikoide und Glukokortikoide am Modell der Mineralokortikoid-Rezeptor Knock-out (MR-KO) Maus. Glukokortikoide steigern in Mineralokortikoid-empfindlichen Geweben, die sowohl den Mineralokortikoid-Rezeptor …
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SCREENING AND IDENTIFICATION OF NEW FOOD DERIVED PEPTIDES WITH MULTI-TARGET CHOLESTEROL-LOWERING ACTIVITY
… of the HMGCoAR. Moreover, P5 was successfully transported by differentiated human intestinal Caco-2 cells through transcytosis, and, during transport, it was partially metabolized in a breakdown fragment (LPKHSDAD, P5-met), which retained the biological activity of the parent peptide. Based on …
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Die Bedeutung des Kaliumkanals KvLQT1 und seiner regulatorischen Untereinheiten für die Epithelfunktion in vivo.
… KCNQ1 bekannt ist, ist in einer Vielzahl von epithelialen Organen exprimiert. Unter anderem konnte er im Gewebe von Niere, Magen und Lunge nachgewiesen werden. Die vorliegende Arbeit beschäftigt sich mit der Funktion dieses Kaliumkanals und seiner regulatorischen Untereinheiten in diesen …