Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Epithelial Regeneration"”.
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Impaired ketogenesis is implicated in intestinal stem cell function and epithelial regeneration in ulcerative colitis
Epithelial repair and regeneration is key to mucosal healing in Ulcerative Colitis (UC). Intestinal stem cells (ISCs) drive this response, proliferating and differentiating from the base of the crypt to regenerate the entire epithelium. ISCs therefore exist in a highly active state and resultantly …
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The Role of Cervical Reserve Cells in Epithelial Regeneration and Homeostasis in the Murine and Human Cervix
… several months and are representative of the epithelial population in vivo. Furthermore, steps were taken towards optimising human cervix organoids. The established in vitro system was exploited along with in vivo samples to further to uncover specific signalling pathways that regulate the …
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YAP/TAZ REGULATES ALVEOLAR REGENERATION AND RESOLUTION OF LUNG INFLAMMATION
… for recovery from these insults to rebuild the epithelial barrier and restore pulmonary functions. Here, we show that sublethal infection of mice with Streptococcus pneumonia, the most common pathogen of community-acquired pneumonia, led to exclusive damage in lung alveoli, followed by alveolar …
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Targeting Endothelial Pathological Calcium Signaling Accelerates Resolution of SARS-CoV-2-Induced ARDS
… can restore barrier function and accelerate lung regeneration. Using complementary murine models of SARS-CoV-2–induced ARDS, including MA10 infection and K18-hACE2 transgenic mice, I evaluated the therapeutic efficacy of a novel synthetic EB3 inhibitor termed Vascular Therapeutics-109. VT-109 …
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The Physiological and Morphological Responses of the Bladder Urothelium to Differential Injury
… Recent research has identified a role for the epithelial lining of the bladder, which is usually targeted by these afflictions, in potentially contributing to enhancing pain. The bladder epithelium also showcases a rapid ability to regenerate after injury.</p><p>Knowledge of the contribution of …
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Radiologic, Histologic and Functional Analysis after Transplantation of Autologous Cultured Chondrocytes into Trachea and Vocal Fold
… showed good tracheal luminal contour, functional epithelial regeneration, and preservation of neocartilage without inflammation, but lacked adequate mechanical stability. Injection laryngoplasty is an option for treatment of glottic insufficiency following vocal fold paralysis, vocal fold atrophy …
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The role of microbial-mediated genotoxicity during pathogenesis
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2027-05-01