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Showing 1 to 1 of 1 for “"Epidermal overdesquamation"”.

  1. Generation and characterization of novel mouse models to validate the role of KLK5 protease in inflammation for pharmacological applications

    … KLK5 hyperactivity is involved in pathological epidermal overdesquamation and inflammation associated with rare diseases, such as the Netherton syndrome (NS). In NS epidermis, genetic deficiency of the LEKTI inhibitor of serine proteases results in unopposed activity of KLK5 (and other serine …

    patras-thes Repository record for Generation and characterization of novel mouse models to validate the role of KLK5 protease in inflammation for pharmacological applications (opens in a new tab)