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Showing 1 to 3 of 3 for “"EphB4"”.
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Role of ephrinB2 and EphB4 in mouse retinal angiogenesis
… the ephrin family, ligand ephrinB2 and receptor EphB4 are known for their ability to distinguish arterial versus venous endothelium upon their expression on the cell surface. Both substances are playing an important role for the formation of the primary vascular network during embryonal …
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Applications of Ephb4 Receptor Specific Peptides In Targeted Cancer Imaging and Therapy
<p>EphB4 receptors, a member of the largest family of receptor tyrosine kinases, are found over-expressed in a variety of tumors cells including glioma cells as well as angiogenic blood vessels. Noninvasive imaging of EphB4 could potentially increase early detection rates, monitor response to …
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The Atom Surface Site Interaction Point Approach to Non-Covalent Interactions
… system of many ligands against a single EPHB4 protein, the AIP approach performed comparably to state-of-the-art free energy perturbation calculations. Therefore, the knowledge of non-covalent interactions obtained using the AIP approach can be used not only to judge promising ligand …