Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 13 of 13 for “"Eotaxin"”.
-
Stat6-vermittelte Genregulation in eukaryontischen Zellen
… der Arbeit bildete die Regulation des Eotaxin-1-Promotors. Eotaxin-1 ist einer der stärksten Rekrutierungsfaktoren für Eosinophile, die eine zentrale Rolle bei der Immunpathologie allergischer Erkrankungen spielen. Mit Hilfe der Daten konnte eine neue Hypothese zur Regulation des …
-
Genetic Polymorphism of Prostanoid Receptors, CRTH2 and TBXA2R in Aspirin Hypersensitivity
… AIA patients had significantly higher serum eotaxin-2 levels than did those with ATA (p=0.034). A significant difference in the genotype frequencies of CRTH2 -466T>C was detected between AIA and ATA patients (p<0.05). The serum eotaxin-2 level was significantly higher in AIA patients carrying …
-
Multi-Pronged Approach to Understanding the Toxicity Associated with CAR T-Cell Therapy
… iv were tested, including secretion of eotaxin-3, scFvs, and a nanobody. While eotaxin-3 and anti-CCR2 scFvs showed limited efficacy, anti-CCL2 constructs were expressed and bound their target, though migration blocking was not reproducible. These studies nevertheless demonstrate …
-
Influence of helminth infection on vaginal immunity
… IL-2 and IL-12) and Type 2 (IL-4, IL-5, IL-13, eotaxin and elevated IgG4/ IgE ratio) immune response in the female reproductive tract in xvi comparison to uninfected women. Type 2 immunity was pronounced in hookworm and Human Papillomavirus co-infected women who maintained an elevated Type 2 …
-
Temporal profile of blood cytokine levels and placental pathology in extremely preterm infants
… compared to groups N, I and V for the following: Eotaxin (p = 0.038), G-CSF (p = 0.023), IFN-γ (p = 0.002), IL-1ra (p < 0.001), IL-4 (p = 0.005), IL-8 (p = 0.010), MCP-1 (p = 0.011), and TNFα (p = 0.002). Post hoc analysis revealed sex differences in group I, with higher median levels of FGF-basic …
-
Chloride Channel 3 (CLC3), an Immune Antiporter in the Migration and Activation of Human Eosinophils in Allergic Asthma
… different blockers and techniques, TGF-β and eotaxin-induced migration and activation of eosinophils were found to be dependent on CLC3. Molecular investigation revealed that TGF-β regulates CLC3 through PKC-δ and SMAD3. Gene analysis disclosed multiple AP-1 binding sites on CLC3 gene, …
-
EOSINOPHILIC INFLAMMATION IN NASAL POLYPOSIS: REGULATION OF INTERLEUKIN 5 AND INTERLEUKIN 5 RECEPTOR α ISOFORMS
… of TGF- β1 and overproduction of IL-5 and eotaxin in NP tissue. Although elevated IgE levels are found in NP, total IgE and IgE antibodies in NP tissue was unrelated to skin prick tests, but correlated with the degree of eosinophilia. In addition, we demonstrated the organisation of …
-
Acute tubulo-interstitial nephritis : clinical profile and pathogenic mechanisms
… CD3+ cells, CD4+ cells, CD8+ cells, CD68+ cells, eotaxin, CCR3, VCAM-1, IL-4 and eosinophil proteins. These results suggest that there is a Th 2 type of inflammatory and immune response in acute tubulointerstitial nephritis. Comparison between the infiltrating cells showed no significant …
-
IMMUNOLOGICAL CHARACTERIZATION OF SEVERE INFERTILE MEN REVEALED ALTERATIONS OF THE LYMPHOID AND MYELOID COMPARTMENTS
… recruitment, such as MCP-1, MIP1b, RANTES, Eotaxin, and IL-8, were detected at lower or comparable concentration in samples from infertile men compared to fertile ones. Peripheral blood The analysis of leucocyte subsets in the peripheral blood revealed a higher frequency of neutrophils in …
-
T Cell Responsiveness Through the Ages: Functional Diversity of Age-Dependent Antiviral Responses
… days 0, 3, and 28, and decreased peripheral eotaxin at study day 28. Third, peripheral myeloid analytes were positively associated with severity based on intake vitals, while cytotoxic natural killer T (NKT) cells were negatively associated. Multiple circulating and upper respiratory …
-
Vitamin D and Immunomodulation in Bronchial Asthma
… Normal T-cell Expressed, and Secreted), Eotaxin, MCP- 1,2,3 (monocyte chemotactic protein). NF-κB (nuclear factor kappa-light-chainenhancer of activated B cells) is a key transcriptional factor that regulates and coordinates the expression of various inflammatory genes and inflammatory …
-
Immunodulation of inflammation in a murine pnemococcal sepsis model
… IFN-g, IL-12 (p40/70), IL-6, IL-1a/b, IL-10, Eotaxin, MCP-1, and MlP-1a/b were attenuated in C57BL/6 LPS-treated mice 12 hours after infection compared to untreated group. Pretreatment with a low dose of LPS also prevented hypoglycemia (glucose level was 149 vs. 45) and liver failure (reduced …
-
L'impatto degli antipsicotici long-acting sui marker della neuroinfiammazione associati alla schizofrenia
… come IL-1β, IL-18, TGF-β1, RANTES, Eotaxina, e la somministrazione di terapia con antipsicotici iniettivi di prima e seconda generazione a rilascio prolungato. Lo studio è stato effettuato su un campione di 18 pazienti con schizofrenia, suddivisi in due gruppi, a cui erano stati …