Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Eomesodermin"”.
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THE ROLE OF T-BET IN LUNG INFECTION
… of T-bet and another homologous T-box factor, Eomesodermin (Eomes), in natural killer cells was observed. To further understand immunomodulatory mechanisms of T-bet, we further explored the regulatory effects of T-bet on Eomes. Together, our results provide the possibility of targeting T-bet …
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Regulation of Anti-Viral Cd8+ T Cell Responses by the Pd-1 Pathway
… involving the transcription factors T-bet and Eomesodermin. As a result, PD-1 deficiency led to the accumulation of terminally-differentiated, but more cytotoxic, exhausted CD8+ T cells. These findings reveal a novel dual role for PD-1 signals during acutely-resolved and chronic viral …
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Memory Potential, Molecular Characterization, and Translational Applications of The Novel Theo/Tceo T Cell Phenotype
… by expression of the T-box transcription factor Eomesodermin (Eomes) and the co-inhibitory receptor Killer Cell Lectin-like Receptor G1 (KLRG1) which we collectively term ThEO.</p> <p>Herein, we demonstrate that the ThEO phenotype constitutes a stable T cell polarity capable of recalling to …
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microRNA expression profile of undifferentiated and differentiating pluripotent cells
… von Mesoderm-Markern, wie z.B. Brachyury, Eomesodermin und Fgf-8, sowie von Keimzelllinien-Markern, wie z.B. Dppa3, und damit die Differenzierung in diese beiden Keimblätter verhindert. Mittels TargetScan Software wurden mehrere mögliche Zielgene des miR-302 Clusters identifiziert. Diese …
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Single-cell genomics in rabbit and mouse elucidate eutherian embryonic development
… factors (TFs) such as Zic2/3, Mix-like 1(Mixl1), Eomesodermin (Eomes), Stat3, and Runx1 in early development. These key TFs are involved in a variety of roles, such as metabolism, as well as the fate decision of mesoderm, and blood development. Constructing an understanding of the stepwise role …
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Eomes Directs the Formation of Spatially and Functionally Diverse Extra-Embryonic Mesoderm Derived Tissues
… progenitors, is the T-box transcription factor Eomesodermin (Eomes). Eomes is expressed early in gastrulation and plays known roles in various extra-embryonic and embryonic tissues, such as the trophectoderm, visceral and definitive endoderm, and various anterior mesodermal tissues. …