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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Enzymkatalyse"”.
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Allosterische Kontrolle von Katalyse- und Rezeptoreigenschaften mehrkerniger Metallkomplexe
Enzymkatalyse wird in der Natur oftmals durch allosterische Regulation kontrolliert. Bei synthetischen Katalysatoren ist diese Regulation noch nicht näher untersucht worden. Im Rahmen der Arbeit wurden drei– und vierkernige Metallkomplexe verschiedener Liganden (L1 – L3) als Modellsysteme für …
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Versuche zur Strukturaufklärung bakterieller Thiouridin Synthetasen
… tRNA (39-mer tRNAPhe, einem Minimalsubstrat der Enzymkatalyse) zu generieren und zu kristallisieren. Die so erhaltenen Kristalle wurden zu röntgenkristallographischen Studien heranzogen.
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Allosterische Metallkomplex-Katalysatoren : Synthesen, Strukturen und reaktionskinetische Untersuchungen
… der katalytischen Aktivität ist ein in der Enzymkatalyse weit verbreitetes Phänomen, wurde aber bei synthetischen Katalysatoren bisher nicht untersucht. Im Rahmen der Arbeitmehrkernige Metallkomplexe als Modellsysteme für allosterische Metalloenzyme untersucht. Die Katalysatoren sind durch …
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Synthese und Charakterisierung von bioabbaubaren Polymeren auf der Basis von Polydepsipeptiden
The thesis deals with the synthesis and characterization of bioresorbable polymers based on polydepsipeptides. Four different types of polydepsipeptide-polyether block copolymers were synthesized via ring-opening polymerization of morpholine-2,5-dione derivatives. The dependence of the macroscopic …
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Fundamental phenomenological description and experimental optimization of gel stabilized biocatalysts in a two-phase system
The lipase from Candida rugosa is immobilized in calcium-alginate hydrogel before been placed in hexane in order to catalyse the esterification of butanol and propionic acid. The consequence of the acidification of the aqueous phase lead to the evolution of the calcium-alginate network to an …
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Development of immobilization and drying methods of enzymes on support particles for enzymatic gas-phase reactions
In this research work, two mesophilic alcohol dehydrogenases namely baker’s yeast alcohol dehydrogenase (YADH) and Lactobacillus brevis alcohol dehydrogenase (LBADH) and one thermophilic alcohol dehydrogenase namely Thermoanaerobacter species alcohol dehydrogenase (ADH T) were immobilized by …
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Elektroenzymatische Synthese mit ionischen Flüssigkeiten
The electrochemical generation, respectively regeneration of redox equivalents represents an interesting alternative to the for this purpose usually applied methods. However, this method has some drawbacks, which make their application as industrial processes economically unfeasible. Especially, …
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Prozessentwicklung für die kontinuierliche dynamisch kinetische Racematspaltung
A dynamic kinetic resolution is an interesting and reasonable extension for a simple kinetic resolution. Especially for the connection of an enzymatic catalysed kinetic resolution and a chemical catalysed racemisation very good results are known from literature. Common compatibility problems …
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Experimentelle Analyse, Modellierung und biochemische Charakterisierung von Ein- und Zweiphasenreaktionen für die technische Biokatalyse
Reaction engineering is a key aspect in the optimisation of chemical reactions. However biocatalysis faces a set of problems while implementing the interdisciplinary methods from biology, thermodynamics, and engineering science. Four issues are of mayor concern: (1) arbitrary simplifications in …
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Mechanistic insights into the PARP10-mediated ADP-ribosylation reaction and analysis of PARP10's subcellular localization
ADP-ribosylation controls many cellular processes, including transcription, DNA repair, and bacterial toxicity. ADP-ribosyltransferases and poly-ADP-ribose polymerases (PARPs) catalyze mono- and poly-ADP-ribosylation, respectively, and depend on a highly conserved glutamate residue in the active …