Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 3840 for “"Enzymes"”.
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The Development of Certain Enzymes and Iso-Enzymes During Normal Pregnancy
… a means of quickly screening maternal serum enzymes in all pregnant women attending the ante=natal clinic. With the exception of γ-glutamyl transpeptidase which was found to originate from liver the source of the increase in maternal serum enzymes is the placenta. Placental specific …
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The activity and dynamics of enzymes
It is generally accepted that enzymes require internal flexibility, or the activation of anharmonic motions, for catalytic activity. However, in general, the timescales and forms of the functionally important motions coupled to progress along the reaction pathway remain poorly understood. A number …
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Glycosidic Enzymes of the Tropaeolum Majus
… of this study is to investigate the hydrolytic enzymes of Tropaeolum majus. This particular plant is the only example of the Tropaeolum genus found in the northern hemisphere. It is the well-known Indian cress or common garden nasturtium.
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Metabolism of testosterone by tissue enzymes
… additional unknown ketonic compounds. These skin enzymes were found to vary quantitatively among different subjects. [TRUNCATED]
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Novel imprinted polymers as artificial enzymes
Derivatives of L-histidine were investigated as suitable models for the Asp-His couple found in the catalytic triad of serine proteases. A combination of molecular dynamics and IH NMR spectroscopy suggested that the most populous conformations of N-acetyl-L-histidine and the N-acetyl-L-histidine …
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Studies of Lipoic Acid Related Enzymes
Using a similar strategy of library construction and screening, I also isolated the Vibrio harveyi acyl-ACP synthetase gene and showed that it encoded a 60.4 KDa protein that shared high homology with medium chain fatty acid-CoA ligases. I expressed the His-tagged protein at a high level in E. coli …
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Biosensor design utilizing particle-bound enzymes
… biosensor format for utilizing particle-bound enzymes.
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Isoflurane : interaction with hepatic microsomal enzymes
lsoflurane interacts with cytochrome P-450 in rat and human hepatic microsomes and the Δ6- and Δ5-desaturases in rat hepatic microsomes. The interaction of isoflurane with cytochrome P-450 results in its metabolism to fluoride ion and organofluorine metabolites. The cytochrome P-450 isozymes …
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Modeling Diiron enzymes for alkanes activation
The synthesis and characterization of a series of ruthenium 'sawhorse' complexes of the type [RU2(IJ-02CRh(CO)4(Lh]' has been successfully carried out. The complexes have been characterized by IR, 1H and 13C NMR spectroscopy, elemental analysis as well as by mass spectrometry.
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Small molecule inhibitors of parasitic enzymes
The work presented in this thesis is threefold:-(i) development of potential novel inhibitors of cysteine proteases from the causative agents of Malaria, African sleeping sickness and Chagas disease, (ii) development of potential new and novel anti-trypanosomal inhibitors of trypanosome alternative …
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tRNA synthetases as potential RNA capping enzymes
(CZ) V naší laboratoři byl nedávno objeven nový typ nekanonických RNA čepiček, obsahujících dinukleosid polyfosfáty. Abychom mohli objasnit jejich fyziologickou roli, je potřeba získat více informací o jejich syntéze v buňkách. Na základě nedávno publikovaných výsledků, dinukleosid polyfosfátové …
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Foamy Virus Enzymes - Activity, Regulation and Resistance
… RNA. The Pol protein, the precursor of the viral enzymes, is translated from a separate mRNA independently of the capsid and matrix proteins. The protease remains covalently bound to the reverse transcriptase, while in orthoretroviruses the protease is cleaved off autocatalytically. Thus, in …
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Biofuel Cell Anode for NAD-Dependent Enzymes
… If we refer back to nature, we have learned that enzymes play a very important role in oxidizing these types of fuels to obtain energy. If we could mimic such processes in a fuel cell, we would be able to harvest the energy of the fuels and convert it into electrical power. There are several …
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Enzymes : the new water/wastewater treatment chemical
Pharmaceuticals and personal care products (PPCPs) are detected routinely in raw and treated municipal wastewater. Conventional wastewater treatment processes are not effective in removing PPCP; therefore, treated wastewater discharges are one of the main entry points for PPCPs into the aquatic …
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X-ray Crystallography of Inositol Dehydrogenase Enzymes
Lactobacillus casei BL23 expresses two enzymes encoded by the genes iolG1 and iolG2. They have been putatively assigned as myo-inositol dehydrogenases by sequence comparison. The enzyme catalyzes the reversible conversion of myo-inositol to scyllo-inosose and the concurrent reduction of NAD+ to …
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Structure Determination of Natural Product Biosynthesis Enzymes
… however characterization of NP biosynthetic enzymes bears immense promise for their utility in NP production. Tremendous advancement in genetic sequencing technology has enabled scientists to decipher biosynthetic gene clusters (BGCs) facilitating interrogation of the synthetic and regulatory …
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