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Showing 1 to 1 of 1 for “"Enzyme mechansim"”.
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Conserved Conformational Dynamics Control PTP1B Enzymatic Activity
… long-accepted paradigm of biochemistry is that enzyme function depends on the three-dimensional (3D) structure. However, this paradigm is changing. Namely, the emerging view is that protein function also depends on intrinsic protein dynamics. Further, while sequence conservation is …