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Showing 1 to 1 of 1 for “"Enzyme kinetics and PK modeling"”.
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IN VITRO AND IN VIVO KINETIC MODELING OF DIAZEPAM METABOLISM
… plays an important role in drug absorption and drug elimination. Therefore, it is crucial to understand the mechanism and kinetics of drug metabolism by various drug-metabolizing enzymes (DMEs). Cytochrome P450 enzymes (CYPs) are responsible for the metabolism of more than 60% of the top 200 …