Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"Enzymatic inhibition"”.
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Nutrient and Stress-Induced Mitochondrial Hyperfusion Regulates Cell Death Pathways
… mitochondrial hyperfusion response. Furthermore, enzymatic inhibition of inosine monophosphate dehydrogenase further blocked this hyperfusion response, indicating a key role of purine biosynthesis in mitochondrial remodelling. The functional role of mitochondrial hyperfusion has been linked to a …
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A Non-Biological Inhibition Based Sensing Technique (NIBS) for the Detection of Halogenated Disinfection By-Products in Water
… a newly developed technique, non-biological inhibition based sensing (NIBS), for the detection of toxic halogenated disinfection by-products in water. NIBS is a chemical amplification method where the analyte of interest inhibits a given catalyzed reaction rather than enhancing the reaction …
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Reevaluating Chlorotoxin Targets: Insights Into Glioblastoma Cell Migration and Neuropilin-1 Binding
… P78 (Ctx residues 27–34) exhibited the strongest inhibition of U-87 MG migration compared to other peptides and full-length Ctx. To investigate the molecular targets of Ctx and its fragments, biophysical techniques were utilized such as nanoDifferential Scanning Fluorimetry (nanoDSF) and Surface …
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A Novel Role for and Potential Therapeutic Targeting of Heme Oxygenase-1 in HIV Neuropathogenesis
… neurotoxin production. HO-1 siRNA knockdown and enzymatic inhibition in HIV-infected macrophages increased supernatant glutamate and neurotoxicity. In contrast, increasing HO-1 expression through siRNA derepression or with pharmacologic inducers, including the CNS-penetrating drug dimethyl …
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Targeting Mitochondrial Proline Dehydrogenase (PRODH) with a Suicide Inhibitor as a Novel Anticancer Strategy
… human breast cancer cells. PRODH knockdown or enzymatic inhibition each inhibited cell growth and induced variable degrees of apoptosis against malignant breast epithelial cell lines (ZR-75-1, DU4475, MCF-7) without affecting immortalized and non-malignant breast epithelial cells (MCF-10A). …
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Exploring the Genomic, Plant Growth Promoting, and Biocontrol Potential of a novum species 'Candidatus Pseudomonas auctus' JDE115 with its description
… and broth assays showed complete fungal inhibition, and scanning electron microscopy confirmed structural damage to fungal sclerotia. JDE115 produces a range of antifungal compounds, including chitinase, glucanase, protease, cellulase, siderophores, hydrogen cyanide, and volatile organic …
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Bioaccessibility and metabolism of anthocyanins: effects of fermentation, encapsulation, and microbiota interactions
… cancer cells, antioxidant activities, and enzymatic inhibition properties. To improve anthocyanin stability during digestion, jabuticaba extract was encapsulated with whey protein (WP) or pea protein (PP) combined with gum arabic (GA). Encapsulation improved anthocyanin bioaccessibility, …
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Exploitation of agricultural and food wastes: from the recovery of bioactive compounds for nutraceutical applications to the production of innovative materials [Valorizzazione di scarti agricoli ed alimentari: dal recupero di composti bioattivi per applicazioni nutraceutiche alla produzione di materiali innovativi]
Le industrie agroalimentari generano un’ingente quantità di rifiuti che, rimanendo insufficientemente sfruttati, comportano problematiche ambientali, economiche e sociali. I gusci delle specie Pistacia vera, Prunus dulcis, Corylus avellana e Juglans regia rappresentano i sottoprodotti più …