Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 23 for “"Enterotoxins"”.
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Detection of staphylococcal enterotoxins in patients with rheumatoid arthritis or closed fracture
… To develop protocols to digest staphylococcal enterotoxins B and C (SEB/SEC), toxic shock syndrome toxin 1 (TSST-1) and alpha haemolysin (AH), members of the pyrogenic toxin superantigen family (PTSAg). To develop a novel mass spectrometry method to analyse and compare urine samples from …
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Studies on the Expression and Regulation of Enterotoxins and Colonization Factors in Enterotoxigenic Escherichia coli (ETEC)
… sub-culturing the gene expression of the two enterotoxins as well as the two CFs were studied in vivo. By also quantifying the transcription levels of the respective genes after in vitro culture we found that there was no significant up- or down-regulation of transcription of the genes …
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Regulation of Arachidonic Acid Pathway and Eosinophilic Inflammation in Chronic Rhinosinusitis/ Nasal Polyposis. Potential Role of Staphylococcus aureus Enterotoxins
… our group, we studied the influence of S. aureus enterotoxins in the regulation of both eosinophilic inflammatory and eicosanoid pathways. We first show that nasal polyposis/aspirin intolerance was associated with increased concentrations of eosinophil-related mediators, as well as of IgE …
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A Multiepitope Subunit Vaccine for Enterotoxigenic Escherichia Coli (ETEC) Expressing LT, STA, STB, and STX2E Toxins
… animals, such as pigs, against ETEC diarrhea. Enterotoxins, including heat-labile (LT), heat-stable type I (STa), heat-stable type II (STb) and shiga-like toxin Stx2e, produced by ETEC strains are the virulence determinants in porcine ETEC-associated diarrhea. These enterotoxins enzymatically …
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Engineering soluble, high affinity T cell receptor domains for detection of staphylococcal and streptococcal exotoxins
… a family of exotoxins including staphylococcal enterotoxins A, B, C (SEA, SEB, SEC), toxic shock syndrome toxin-1 (TSST-1) and streptococcal pyrogenic exotoxins (SpeA, SpeC) that possess superantigenic properties, by virtue of which they stimulate a large fraction of an individual’s T cells, …
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Molecular typing of virulence genes in enterotoxigenic Bacillus cereus
… food due to the production of emetic toxins and enterotoxins. SYBR Green I is used as an intercalating dye and its florescence increases as a result of DNA amplification during real-time PCR. A second-derivative plot is obtained at the end of the PCR run, where amplicons are differentiated based …
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Engineering the T Cell Receptor to Protect Host Cells in Superantigen-Induced Septic Shock
… T cell activation. A class of SAgs is the enterotoxins of the bacterium Staphylococcus aureus, including B and C3 (SEB and SEC3, respectively). These toxins maintain an ability to bind many different variable domains of the TCR beta chain (Vbeta), resulting in stimulation of large subsets …
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Análise das condições microbiológicas de queijos minas frescal vendidos em João Pessoa-PB
… high scores with great possibility of producing enterotoxins. High counts of microorganisms identified (mesophilic, psicotrophic coliforms) indicate that hygiene and sanitary conditions of production were unsatisfactory. Thus, there is a commitment on the final quality of these cheeses.
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Comparison of Staphylococcus aureus isolates associated with food intoxication with isolates from human nasal carriers and human infection
… results from oral intake of staphylococcal enterotoxins leading to violent vomiting, diarrhea and cramps shortly upon ingestion. The aim of the present study was to compare isolates associated with SFP to isolates collected from cases of human nasal colonization and clinical infections in …
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Investigations of Carbapenem-resistant Klebsiella species and associated clinical considerations
… cluster encodes for tilimycin and tilivalline, enterotoxins previously thought only to be carried by K. oxytoca strains. Incorporation of antimicrobial resistance and virulence gene data showed hypervirulent, multidrug-resistant K. pneumoniae strains encoding both aerobactin and rmpA (the …
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Importanza prognostica delle citochine e loro ruolo nell'immunomodulazione: risultati di studi sperimentali in vivo e in vitro
… different cytokines were expressed depending on enterotoxins produced, justifying a different behaviour of the microrganism in the mammal gland. In the second one, bone marrow cells derived incubated with murine lymphocytes with colostrum products have shown various cluster of differentiation …
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Characterisation of Guanylin and Uroguanylin in the Digestive System
… being the receptor for diarrheagenic bacterial enterotoxins. Observed human mutations in the receptor cause its hyperactivation or inactivation, leading to familial syndromes of diarrhoea and meconium ileus, respectively. The function of guanylin and uroguanylin is not restricted to intestinal …
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EOSINOPHILIC INFLAMMATION IN NASAL POLYPOSIS: REGULATION OF INTERLEUKIN 5 AND INTERLEUKIN 5 RECEPTOR α ISOFORMS
… with the presence of IgE specific to S. aureus enterotoxins (SAEs), colonization with S. aureus, and increased eosinophilic inflammation in a relevant subgroup of NP patients. The ultimate way to test the role of IL-5 and eosinophils in the pathogenesis of nasal polyposis, is by antagonizing …
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The role of mucin in establishment of Escherichia coli in porcine small intestine
… coli P-155 produced heat-stable and heat-labile enterotoxins during growth in both mucin medium and fresh mucosal scrapings medium. E. coli utilized total hexose and protein in mucin medium at comparable levels (6 to 10%). Increases in reducing end groups (0.28 μ moles/ml) and free amino sugar …
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Characterization of the Factors Associated with SCCmec Mobility in Staphylococcus Aureus
… frames found in this region were homologous to enterotoxins, restriction-modification enzymes, and transposases. Several open reading frames that have not been previously reported in staphylococci were also present in this region. 28 out of the 42 isolates examined did not contain the attachment …
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Epidemiology, molecular characterisation and toxin regulation of enterotoxigenic Escherichia coli (ETEC) isolated from children with diarrhoea
… factors in the regulation of the ETEC enterotoxins. We studied the prevalence, seasonality, antibiotic resistance and severity of disease of diarrhoeas caused by DEC in children aged less than five years in two areas in Bolivia over a period of four years (2007-2010). We showed that …
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Detection and further characterisation of the toxins and associated genes of Bacillus cereus
… the emetic toxin (cereulide) and at least five enterotoxins. The relative importance of these metabolites to the pathogenicity of B. cereus strains has not been fully elucidated. The major goals of this project were to evaluate existing toxin detection methods, develop improved methods of …
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Peptide ligands that bind to staphylococcal enterotoxin B (SEB)
… to SEB, but only weakly to other staphylococcal enterotoxins that share sequence and structural homology with SEB. Using column affinity chromatography with an immobilized YYWLHH stationary phase, it was possible to separate SEB quantitatively from Staphylococcus aureus fermentation broth, a …
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