Global ETD Search
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Showing 1 to 3 of 3 for “"Enteroids"”.
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Human enteroids as a model for infectious disease
… epithelial cells was developed, termed enteroids. Human enteroids are a powerful tool for understanding the complex interactions between human intestinal epithelial cells and enteric pathogens. We used human enteroids to investigate infection of intestinal epithelial cells by two …
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Role of cytokine IL-15 in the homeostasis of the intestinal epithelium and inflammatory bowel diseases
… but not in WT mice. Using mouse in vitro crypt enteroids from WT and Il15-deficient mice, this study demonstrates that exogenous mIL-15 promoted increased mRNA levels of the Lgr5 stem cells marker only in mutant enteroids, but not other epithelial cell linage markers tested, suggesting a role of …
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ENGINEERING STEM CELLS AND ORGANOIDS ON A CHIP FOR THE STUDY OF HUMAN HEALTH AND DISEASE
… of vascularized, perfusable IBD patient enteroids for the study of immune responses in IBD. Finally, we present an alveologenesis-on-a-chip model that enables simulation of the fetal breathing movement-induced mechanical forces. The proposed system was then utilized to understand how …