Global ETD Search
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Showing 1 to 15 of 15 for “"Enterohemorrhagic Escherichia coli"”.
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Characterization of QSEA and QSED in the Quorum Sensing Cascade of Enterohemorrhagic Escherichia Coli
Enterohemorrhagic E. coli O157:H7 (EHEC) is an enteric pathogen that has been implicated in many outbreaks of bloody diarrhea worldwide. EHEC senses its environment through quorum sensing, a mechanism by which bacteria use chemical signals, termed autoinducers, to regulate key genes. In the …
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Survival of Enterohemorrhagic Escherichia Coli O157:H7 During the Manufacture and Curing of Cheddar Cheese
<p>The ability of enterohemorrhagic Escherichia coli O157:H7 to survive a standard Cheddar cheese manufacturing process was determined using active lactic mesophilic starter culture and subsequent curing. This strain of E. coli can survive under more adverse intrinsic and extrinsic conditions than …
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The Role of Host Hormones and Metabolites in the Regulation of Virulence in Enterohemorrhagic Escherichia coli (EHEC)
… bacteria, including the enteric pathogen enterohemorrhagic Escherichia coli O157:H7 (EHEC) that causes hemorrhagic colitis, sense diverse environmental signals, and use them as cues for differential gene regulation and niche adaptation. This allows for a temporal and energy efficient …
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Structural and Mechanistic Roles of Novel Chemical Ligands on Quorum Sensing Transcription Regulator SdiA in Enterohemorrhagic Escherichia coli
… (AHLs) [1]. However, some bacteria such as Escherichia coli (E. coli) do not produce AHLs and, therefore, their quorum sensing LuxR-type proteins are thought to be regulated by AHLs from other bacteria [2-4]. These sub-family of LuxR proteins known as LuxR solos can also regulate and detect …
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The Functional Characterization of the LysR-Type Transcriptional Regulator QseD and the SorC-Type Transcriptional Regulator LsrR in Enterohemorrhagic Escherichia coli
Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a human pathogen responsible for numerous outbreaks of hemorrhagic colitis (HC) and hemolytic uremic syndrome (HUS) throughout the world. EHEC is able to sense and respond to biotic cues from its environment, such as the human host produced …
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Evaluation of a gold nanoparticle platform as highly immunogenic and protective therapy against Burkholderia mallei, B. pseudomallei, and Enterohemorrhagic Escherichia coli O157:H7
… AuNP-coupled proteins in a colonization model of Enterohemorrhagic Escherichia coli (EHEC). Furthermore, we showed that vaccination with AuNP-coupled to EHEC-specific antigens elicits strong systemic and mucosal response associated with protection against EHEC colonization. This work proposes to …
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Proteomics approach on the identification of virulence factors of enteropathogenic and enterohemorrhagic Escherichia coli (EPEC and EHEC) and further characterization of two effectors: EspB and NleI
Enteropathogenic and enterohemorrhagic Escherichia coli (EPEC and EHEC) are two closely related human pathogens responsible for food-borne epidemics in many countries. Several virulence factors together with some putative proteins were identified from the extracellular proteomes of EPEC and EHEC. …
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The Characterization of the Fucose Sensing Kinase (FUSK) and the Fucose Sensing Response Regulator (FUSR) and Their Role in Virulence Regulation in Enterohemorrhagic Escherichia Coli O157:H7
EHEC causes outbreaks of bloody diarrhea worldwide, by colonizing the human large intestine, where it forms attaching and effacing (AE) lesions on the intestinal epithelium. AE lesion development requires the presence of the locus of enterocyte effacement (LEE) that encodes for a molecular syringe, …
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Biochemical Studies of EA22, A Protein Involved in The Bacteriophage Lysogenic-Lytic Decision and the Virulence of Clinically Relevant Serotypes of E. Coli
Enterohemorrhagic Escherichia coli (EHEC) infections are associated with short term gastrointestinal problems, but in some cases, it can lead to more life-threatening conditions. The pathogenicity of EHEC Is supported by an endogenous, dormant bacteriophage that persists in the bacterium as a …
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Genetic mechanisms contributing to antimicrobial resistance: gene repression in Mycobacterium, gene transfer in Salmonella, and phage sensitivity in Escherichia
… resistant cells. Mycobacterium, Salmonella, and Escherichia are all capable of causing disease, and each demonstrates increasing resistance to conventional antibiotic treatment. Understanding the genetic mechanisms that regulate antibiotic resistance are critical in developing new antimicrobials …
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Structural Analysis of Cycle Inhibiting Factor from Pathogenic Escherichia Coli
… modulate host cell biology. Enteropathogenic and enterohemorrhagic Escherichia coli (EPEC and EHEC) use a type III protein secretion system (T3SS) to inject microbial proteins into host cells. These translocated proteins possess a diverse array of biochemical activities, reprogramming eukaryotic …
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Studies of EHEC and the complement system in renal diseases
… HUS may be associated with infection caused by Enterohemorrhagic Escherichia coli (EHEC) or with complement dysfunction due to complement mutations or auto-antibodies (atypical HUS, aHUS). EHEC is a non-invasive highly virulent bacterium. In order to gain access to the circulation it first …
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Regulation of Host Immune Responses by Toll-Interacting Protein During Citrobacter rodentium Infection
… cause of death in children. Diarrheic enterocolitis can be caused by attaching/effacing (A/E) pathogens like enteropathogenic and enterohemorrhagic Escherichia coli (EPEC and EHEC). Citrobacter rodentium (CR), a murine A/E pathogen, mimics EPEC and EHEC infections, causing goblet cell …
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The Functional Characterization of QSEC a Bacterial Adrenergic Receptor and the LuxR Homologue SDIA in EHEC
Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a human pathogen responsible for outbreaks of hemorrhagic colitis (HC) and hemolytic uremic syndrome (HUS). The histidine sensor kinase QseC is an inner membrane adrenergic receptor which responds to the bacterial signal autoinducer-3 (AI-3) and …
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Interplay Between Tryptophan Metabolites and the Virulence Factors of Enteric Pathogens
… an invading food-borne pathogen such as Enterohemorrhagic Escherichia coli (EHEC), which causes gastroenteritis by primarily colonizing the human colon, sense these small molecules and respond in a way that is conducive for its colonization and virulence gene expression. The role of these …