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Showing 1 to 20 of 43 for “"Enterocyte"”.

  1. Identification and characterization of an enterocyte receptor for group A porcine rotavirus

    … A porcine rotavirus and MA-104 cells or porcine enterocytes. A variety of glycoconjugates and cellular components were screened for their ability to block rotavirus binding to cells. During these experiments a crude ganglioside mixture was observed to specifically block rotavirus binding. …

    uiuc Repository record for Identification and characterization of an enterocyte receptor for group A porcine rotavirus (opens in a new tab)

  2. Regulatory Balance Between the Peptide Trasporter, Pept1, and Amino Acid Transporter Gene Expression in the Enterocyte

    … membrane-associated transporters into and out of enterocytes either in their free form or in the form of peptides. The peptide transporter, PepT1, is thought to be the major facilitator of peptide transport in the enterocyte. It is unknown if the peptide transporters and free amino acid …

    vt Repository record for Regulatory Balance Between the Peptide Trasporter, Pept1, and Amino Acid Transporter Gene Expression in the Enterocyte (opens in a new tab)

  3. The Modulating Effects of Dietary Fiber and Short-Chain Fatty Acids on Enterocyte Differentiation, Maturation and Turkey Coronavirus Infection

    … This is thought to be associated with enterocyte maturation and receptor protein expression. One of the factors that can influence differentiation and maturation of enterocytes is the availability of short-chain fatty acids (SCFA) in the intestinal lumen. These compounds are by-products …

    vt Repository record for The Modulating Effects of Dietary Fiber and Short-Chain Fatty Acids on Enterocyte Differentiation, Maturation and Turkey Coronavirus Infection (opens in a new tab)

  4. Beschreibung und Charakterisierung einer neuen Pathogenitätsinsel, integriert in das selC-Gen von "Locus of enterocyte effacement"-negativen, Shiga-Toxin-produzierenden Escherichia coli

    … konnte die Pathogen-itätsinsel LEE (locus of enterocyte effacement) nachgewiesen werden. Der LEE ist stromabwärts des Gens für eine Selenocystein-tRNA (selC) ins Chromosom integriert. Ziel der vorliegenden Arbeit war die Charakterisierung von STEC, denen der LEE fehlt und die funktionelle …

    wurz-thes Repository record for Beschreibung und Charakterisierung einer neuen Pathogenitätsinsel, integriert in das selC-Gen von "Locus of enterocyte effacement"-negativen, Shiga-Toxin-produzierenden Escherichia coli (opens in a new tab)

  5. The Role of OSTalpha/beta in Bile Acid and Lipid Metabolism

    … of intestinal cholesterol absorption. Ileal enterocyte Fgf15 mRNA expression was not significantly increased, but ileal levels of FGF15 protein was increased almost 10-fold in Osta-/- mice, and total ileal FGF15 protein levels are further elevated to 20-fold due to the increase in ileal …

    wfu Repository record for The Role of OSTalpha/beta in Bile Acid and Lipid Metabolism (opens in a new tab)

  6. FEXOFENADINE AND ORGANIC ANION TRANSPORTING POLYPEPTIDES (OATPs): TRANSPORT AND DRUG-DRUG INTERACTIONS

    … and that this interaction was occurring at an enterocyte-expressed OATP. This interaction was reproduced and studied using in vitro model systems. In Specific Aim 1, a specific LC-MS/MS method was developed and validated for the quantification of fexofenadine and the other four probe drugs for …

    ku Repository record for FEXOFENADINE AND ORGANIC ANION TRANSPORTING POLYPEPTIDES (OATPs): TRANSPORT AND DRUG-DRUG INTERACTIONS (opens in a new tab)

  7. MECHANISMS OF INTESTINAL CHOLESTEROL ABSORPTION AND TRANSPORT IN MOUSE THORACIC LYMPH DUCT LIPOPROTEINS

    … 2 (ACAT2). We hypothesized that, in the enterocyte, ACAT2 cholesterol esterification increases cholesterol absorption efficiency by providing the cholesterol esters (CE) for incorporation into chylomicrons and that G5/G8 limits both phytosterol and cholesterol absorption by reducing …

    wfu Repository record for MECHANISMS OF INTESTINAL CHOLESTEROL ABSORPTION AND TRANSPORT IN MOUSE THORACIC LYMPH DUCT LIPOPROTEINS (opens in a new tab)

  8. Studies on the role of hephaestin and transferrin in iron transport

    … implicated in the export of iron from duodenal enterocytes into blood. These ferroxidases supply transferrin, the iron-carrier protein in plasma, with Fe(III). Transferrin circulates through blood and delivers iron to cells via the transferrin receptor pathway. Due to the insoluble and reactive …

    ubc Repository record for Studies on the role of hephaestin and transferrin in iron transport (opens in a new tab)

  9. Investigating the potential utilisation of black soldier fly (Hermetia illucens) as an alternative protein source in tilapia and carp feed

    … while intraepithelial lymphocytes abundance and enterocyte microvilli length were elevated only at 40% BSF meal. Posterior intestinal endochitinase A, slc6a18, and cytokines (il1β, tnfα, il10) in either the intestine or head kidney were not significantly affected, but slc15a1a was upregulated at …

    plymouth Repository record for Investigating the potential utilisation of black soldier fly (Hermetia illucens) as an alternative protein source in tilapia and carp feed (opens in a new tab)

  10. Dietary carbohydrates influence the structure and function of the intestinal alpha-glucosidases

    … in Caco-2 cells that sorts more quickly to the enterocyte surface to act as a digestive enzyme. As this finding suggested a maltose sensing ability of small intestinal enterocytes, molecular mechanisms associated with the maturation and trafficking of HMW SI were further investigated. A …

    purdue-thes Repository record for Dietary carbohydrates influence the structure and function of the intestinal alpha-glucosidases (opens in a new tab)

  11. P53 Drives A Transcriptional Program That Elicits A Non-Cell-Autonomous Response and Alters Cell State In Vivo

    … cell state leading to a new proximal enterocyte population enriched for genes within oxidative phosphorylation pathways. In addition, a population of active CD8+ T cells was recruited. Combined, this study provides a comprehensive profile of the p53 transcriptional response <em>in …

    uthsc Repository record for P53 Drives A Transcriptional Program That Elicits A Non-Cell-Autonomous Response and Alters Cell State In Vivo (opens in a new tab)

  12. Cellular subversion: towards a complete repertoire of type-III secretion system effectors in enterohaemorrhagic Escherichia coli O157:H7

    … effectors that are encoded within the locus of enterocyte effacement (LEE) have been studied extensively. This study aimed to characterise a selection of recently discovered non-LEE-encoded effectors using a variety of model systems. Firstly, a β-lactamase translocation assay was used to …

    birmingham Repository record for Cellular subversion: towards a complete repertoire of type-III secretion system effectors in enterohaemorrhagic Escherichia coli O157:H7 (opens in a new tab)

  13. Identification and Characterization of APOBEC1 mRNA Editing Targets: A Transcriptomics Approach

    … B (apoB) transcripts of small intestine enterocytes. APOBEC1-mediated cytidine to uridine editing generates an inframe stop codon and results in translation of a truncated apoB isoform with distinct functions in lipid transport. Other physiological mRNA targets of APOBEC1 editing have …

    rockefeller Repository record for Identification and Characterization of APOBEC1 mRNA Editing Targets: A Transcriptomics Approach (opens in a new tab)

  14. Investigating the Spatiotemporal Variation in Functional Markers, Gut Metabolites and Ethanol Toxicity in In Vitro Cultures of the Rat Jejunum and Hepatocytes

    … proximal, medial and distal jejunum. Markers of enterocyte, goblet cell and Paneth cell function in the jejunum followed in vivo – like spatial trends reported for the entire small intestine. Jejunum explants were integrated with hepatocytes to model the intestine-liver axis. Integration of …

    vt Repository record for Investigating the Spatiotemporal Variation in Functional Markers, Gut Metabolites and Ethanol Toxicity in In Vitro Cultures of the Rat Jejunum and Hepatocytes (opens in a new tab)

  15. The Path to an Orally Administered Protein Therapeutic for the Treatment of Diabetes Mellitus

    … and the inability to passage the enterocyte. Herein we report the potential use of vitamin B<sub>12</sub> for the oral delivery of protein therapeutics.</p> <p>We first investigated the ability of insulin to accommodate the attachment of B<sub>12</sub> at the B1 vs. B29 amino acid …

    syracuse-diss Repository record for The Path to an Orally Administered Protein Therapeutic for the Treatment of Diabetes Mellitus (opens in a new tab)

  16. The intestinal absorption of n-3 and n-6 polyunsaturated fatty acids: proposed mechanisms from studies using human Caco-2 cells.

    … intestine. For this mechanistic study, a human enterocyte cell model (Caco-2 cells) was used. A careful attention has been taken on the specific parameters that influence the transport characteristics of the Caco-2 cells and the accessibility of the fatty acids to the absorption site. The …

    rgu Repository record for The intestinal absorption of n-3 and n-6 polyunsaturated fatty acids: proposed mechanisms from studies using human Caco-2 cells. (opens in a new tab)

  17. Pharmacokinetics and Biological Mechanisms of Drug Outcomes in Type 2 Diabetes Mellitus

    … to local factors within the lumen or enterocyte.<br/><br/>Secondly, a recruit-by-genotype, double-blind, randomised, placebo-controlled, crossover study to determine the impact of OCT1 genotype and the use of OCT1 inhibiting drugs on metformin intolerance, has identified a significant …

    dundee Repository record for Pharmacokinetics and Biological Mechanisms of Drug Outcomes in Type 2 Diabetes Mellitus (opens in a new tab)

  18. Intestinal absorption barriers as modelled by p-glycoprotein and cytochrome p450 a34 in caco2 cells

    … two populations of Caco-2 cells influence their enterocyte-like characteristics. Caco-2 cells of passage number >90 from Novartis pharmaceutical company possess higher levels of expression of alkaline phosphatase and P-glycoprotein and a greater cellular uptake of Gly-1.-Pro than those of passage …

    aston Repository record for Intestinal absorption barriers as modelled by p-glycoprotein and cytochrome p450 a34 in caco2 cells (opens in a new tab)

  19. The Characterization of the Fucose Sensing Kinase (FUSK) and the Fucose Sensing Response Regulator (FUSR) and Their Role in Virulence Regulation in Enterohemorrhagic Escherichia Coli O157:H7

    … requires the presence of the locus of enterocyte effacement (LEE) that encodes for a molecular syringe, a type three secretion system (T3SS), which translocates effectors to the host cell. Expression of the LEE is controlled by the AI-3/Epi/NE interkingdom signaling cascade. The …

    utswmed Repository record for The Characterization of the Fucose Sensing Kinase (FUSK) and the Fucose Sensing Response Regulator (FUSR) and Their Role in Virulence Regulation in Enterohemorrhagic Escherichia Coli O157:H7 (opens in a new tab)

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