Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 2531 for “"Engineered"”.
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Engineered Vesicles for Perchlorate Degradation
This study demonstrates the use of engineered vesicles to reduce perchlorate. Specifically, cell-free extracts containing perchlorate reductase and chlorite dismutase enzymes were encapsulated in a triblock copolymer vesicle functionalized with the outer membrane porin OmpF. The porin allows for …
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Electrospun Tissue Engineered Vascular Grafts
ePTFE and Dacron vascular grafts are successful in large diameter applications but provide poor outcomes in small diameter (<6 mm) applications. Occlusion, poor cell ingrowth and a mismatch of compliance compared to the native vessel, cause failure to the current synthetic grafts. Spontaneous …
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Electrospun Tissue Engineered Vascular Grafts
ePTFE and Dacron vascular grafts are successful in large diameter applications but provide poor outcomes in small diameter (<6 mm) applications. Occlusion, poor cell ingrowth and a mismatch of compliance compared to the native vessel, cause failure to the current synthetic grafts. Spontaneous …
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Molecular imaging with engineered physiology
… contrast. Highly potent vasoactive peptides are engineered to respond to specific biomolecular phenomena of interest at nanomolar concentrations by inducing dilation of the microvasculature, increased local bloodflow, and consequently, large changes in T₂*-weighted MRI contrast. This principle is …
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DRUG ELUTING TISSUE ENGINEERED VASCULAR GRAFTS
Electrospun Tissue Engineered Vascular Grafts (TEVG) have been synthesized with variable success. TEVG ≤5mm in diameter have had limited success due to poor patency outcomes with high rates of restenosis secondary to a phenomenon called Intimal Hyperplasia (IH). We have performed previous animal …
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Biomolecular engineered sensors for diagnostic applications
Electrochemistry is a powerful technique that offers multiple possibilities and which is in constant evolution. Simple modifications of the electrode surface can result in an improvement of the selectivity and sensitivity of the method. However some situations require more complex modifications …
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Advanced Electrohydrodynamic Atomisation Engineered Microneedle Coatings
Transdermal drug delivery (TDD) is an emerging field in the pharmaceutical remit compared to conventional methods (oral and parenteral). Microneedle (MN) based devices have gained significant interest as a strategy to overcome the skins formidable barrier; the stratum corneum and enhance drug …
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Engineered quantum dots for infrared photodetectors
… work investigates two approaches for shape engineered QDs: (1) Selective capping techniques of Stranski-Krastanov QDs, and (2) Growth of Sub-Monolayer (SML) QDs. Using Molecular Beam Epitaxy (MBE) growth, engineered QDs have been demonstrated with improved dot geometry and 3D quantum …
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Engineered Alumina / Silicon Carbide Laminated Composites
… fabricated and thoroughly characterized. Five engineered ceramic laminates with peculiar layers combination that is able to promote the stable growth of surface defects before final failure were also designed and produced. By changing the composition of the stacked laminae and the architecture …
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Fermi Mixtures: Effects of Engineered Confinements
In this thesis we first review the theory of the normal state of the unitary Fermi gas at T = 0 and the main properties of the normal-to-superfluid transition. Then we study the trapped gas under adiabatic rotation, i.e., avoiding the formation of vortices. We show that for polarized systems the …
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Engineered Polydopamine Nanocarriers for Biomedical Applications
Despite significant advancements in the field of nanomedicine and the design of drug nanocarriers, several critical challenges persist. These include limited cargo delivery due to uncontrolled drug release, off-target toxicity, premature aggregation, and rapid clearance of nano-formulations. Among …
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Cryopreservation of tissue engineered skeletal muscle
Tissue engineered skeletal muscle plays an important role not only in the field of regenerative medicine, but also in emerging areas such as soft robotics, organ-on-a-chip models of disease, and drug testing. However, further expansion of the applications of tissue engineered skeletal muscle models …
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Understanding Genomes Through Engineered Structural Variation
… sites into a single human genome. These engineered cell lines provided a latent substrate for large-scale genome randomization. After induction with Cre recombinase, I mapped thousands of deletions, inversions, extrachromosomal circular DNA, translocations, and fold- back inversions and …
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Printing protein-engineered paper for biosensors
… for the direct formation and patterning of engineered paper. An analytical model based on incompressible cake filtration theory was derived to predict the final thickness of the printed paper as a function of printing parameters and showed good agreement with the experimental data. This …
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Engineered microneedles for transcutaneous vaccine delivery
… nonhuman primates have indicated the promise of engineered microneedle approaches for successful translation to humans. Overall, these findings provide a strong basis for the continued development of similar vaccination strategies for the comprehensive transformation of conventional vaccination …
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Biomechanical properties of engineered collagen scaffolds
… on the stiffness of collagen scaffolds. Engineered non-crosslinked and dehydrothermally crosslinked chondroitin-6-sulfate collagen scaffolds were hydrated and loaded in tension, and their mechanical properties were compared. It was found that non-crosslinked scaffolds experience an …
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Strain-engineered CMOS-compatible Ge photodetectors
The development of CMOS-compatible photodetectors capable of operating throughout the entire telecommunications wavelength spectrum will aid in the integration of photodetectors with Si microelectronics, thus offering a low cost platform for high performance photoreceivers. This thesis demonstrates …
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