Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 269 for “"Energy Metabolism"”.
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Energy metabolism and aging
… a delayed incidence of cancer, and have improved energy metabolism. While the extended lifespan and the many characteristics of an extended healthspan have been known for some time in Ames dwarf mice, the revelation that dwarf mice have improved energy metabolism was less than a decade ago. This …
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NOTCH SIGNALING REGULATES ADIPOGENESIS AND ENERGY METABOLISM
… which are the primary default storage sites of energy surplus. Another two types of adipocytes can also be found in human: beige and brown adipocytes. In opposite to white adipocytes, beige and brown adipocytes ameliorate obesity by burning lipids for thermogenesis. Thus, an increase in …
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EFFECTS OF HISTONE DEACETYLASE INHIBITORS ON ENERGY METABOLISM
… genes in mitochondrial biogenesis and oxidative metabolism, involving enzymes, such as members of the histone deacetylase (HDAC) family, in particular those belonging to class I and class II, which modulate post-translational modifications on target proteins. The current knowledge on HDACs is …
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Modeling Nitrogen and Energy Metabolism in the Bovine
… of the Molly cow model predictions of ruminal metabolism and nutrient digestion when simulating dairy and beef cattle diets, 2) advance representations of N recycling between blood and the gut and urinary N excretion in the model, 3) improve the representation of pH and to refit parameters …
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Crebh, A Novel Liver Clock Keeper For Energy Metabolism
… to regulate hepatic acute-phase response and energy homeostasis under stress conditions. Here, we demonstrate that CREBH is regulated by the circadian clock and functions as a diurnal regulator of hepatic lipid and glucose metabolism. CREBH is required to maintain circadian profiles of blood …
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Biological variation in basal metabolic rate and energy metabolism
… aspects of nutrition, particularly total daily energy expenditure (TDEE) and basal metabolic rate (BMR). The impact of ethnicity on biological variation on certain aspects of energy metabolism has been investigated. Predictive equations to estimate BMR were published by the FAOIWHOIUNU (1985) in …
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Regulation of Energy Metabolism by Fructose in the Liver
In conclusion, fructose feeding induced a broader range of genes than previously identified with simultaneous increase in glycogen and triglycerides in liver. SREBP-1 and ChREBP, and possibly FoxO1, likely mediate gene induction by dietary fructose. The study also suggests that further ChREBP …
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CARDIAC ENERGY METABOLISM IN ISCHAEMIA AND TYPE 1 DIABETES
… This leads to a remodelling of cardiac metabolism, which can exacerbate production of damaging reactive oxygen species and tissue necrosis upon reperfusion. In a different paradigm of metabolic disease, the type-1 diabetic heart becomes more dependent upon the oxidation of fatty acids …
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Brain energy metabolism: development and application of novel live methodologies
… thesis investigates methods of studying brain energy metabolism with a specific focus on the substrates oxygen and glucose. It details the in vitro development and in vivo characterisation of microelectrochemical sensors for the detection of brain tissue oxygen, and the in vivo characterisation …
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The Effects of Three Endurance Training Programs on Energy Metabolism
Made available in DSpace on 2014-12-10T18:06:47Z (GMT). No. of bitstreams: 1 6607747.pdf: 8210470 bytes, checksum: 50d921e7a046124483e8479210e2bd4b (MD5) Previous issue date: 1966
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A metabolic profiling approach to human disorders of energy metabolism
… of biochemical reactions known collectively as metabolism is essential for life, and dysfunction in parts of this network causes human disease - both rare, inherited disorders and common diseases such as diabetes mellitus. The study of metabolic disease depends upon quantitative methods which …
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The Relationship of Selected Tests With Energy Metabolism and Swimming Performance
Made available in DSpace on 2014-12-04T21:57:05Z (GMT). No. of bitstreams: 1 0006989.pdf: 10206717 bytes, checksum: fc86f360ca2c9a1bbbed89bbdb09875c (MD5) Previous issue date: 1953
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The role of adiponectin and the adipocyte in energy metabolism and inflammation
… role of adiponectin in modulating fatty acid metabolism and inflammation in the pig. In the first study, we cloned and sequenced the porcine adiponectin open reading frame and evaluated the regulation of adiponectin, in vitro and in vivo. The porcine sequence shares approximately 88, 86, 85 …
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The Role of Energy Metabolism in Maximal Performance Facilitated by Informational Cues
Made available in DSpace on 2014-12-10T18:06:39Z (GMT). No. of bitstreams: 1 6500872.pdf: 5967349 bytes, checksum: c8283298958edfe06f93800222ac673b (MD5) Previous issue date: 1964
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Understanding and ameliorating perturbations of human cerebral energy metabolism after major trauma
… brain injury (TBI) dysfunction of cerebral energy metabolism can cause further injury to the traumatised brain – resulting in worse patient morbidity, or death. Using the modalities of cerebral microdialysis, 13C labelled high-resolution nuclear magnetic resonance (NMR) and in-vivo 31P …
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MFSD7C: A Solute Carrier Linking Heme and Calcium in Mitochondrial Energy Metabolism
Major Facilitator Superfamily Domain-Containing 7C (MFSD7C) is an orphan solute carrier. In humans, loss-of-function mutations in MFSD7C cause Fowler syndrome, an often prenatally lethal disorder that affects brain development and angiogenesis. MFSD7C and its closely related paralog MFSD7B, have …
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Energy metabolism in skeletal muscle: mechanistic insights into mitochondrial function and growth
Skeletal muscle metabolism is critical to understanding the efficiency of muscle growth for the global meat industry. As such, there are many contributing factors that can influence muscle growth yet there are still basic molecular mechanisms that remain unexplored. Specifically, the involvement of …
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Platelet Function and Energy Metabolism During Storage in a Well-Defined Experimental Medium
<p>The most significant problem in maintaining platelet viability during storage is the decrease in pH resulting from accumulation of lactic acid formed by platelet anaerobic glycolysis. This study investigates nutrient alternatives to glucose for maintenance of morphology and functional integrity …
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Nonlinear Dynamics of Microcirculation and Energy Metabolism for the Prediction of Cardiovascular Risk
… production of ATP (adenosine triphosphate) energy. In this work, these methods were combined with iontophoresis and PORH (post-occlusive reactive hyperaemia) reactive tests to assess skin microvascular function and oxidative stress in mice and human subjects. The main focus of the research …
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