Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Endotoxin-induced"”.
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Ketogenic Diet is Protective During Endotoxin-Induced Lung Injury
… those on a control diet during a murine model of endotoxin-induced lung injury, induced by intratracheal lipopolysaccharide (LPS) injection. Utilizing a proteomic-based array, ion chromatography–mass spectrometry (IC-MS), and multiplex assays in bronchial alveolar lavage fluid, as well as immune …
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Endotoxin-induced microRNA expression in equine peripheral blood mononuclear cells
… responses. miR-155 is the principal LPS-induced miRNA in horses. Bioinformatic target predictions support roles in regulation of innate and adaptive immune responses including TLR4 signaling, as in humans. It is thus likely to influence the acute inflammatory response to LPS. Further …
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Inflammation, Phagocytosis and Effect of Flunixin Meglumine During Endotoxin-Induced Mastitis (Therapy, Prostaglandins)
The objectives were to determine the following in endotoxin-induced mastitis: (1) milk concentrations of thromboxane B(,2) (TXB(,2)) and prostaglandin F(,2(alpha)) (PGF(,2(alpha))); (2) the pharmacokinetics of flunixin meglumine in lactating cattle; (3) the clinical efficacy of the flunixin …
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Fumarate Inhibits TNF-α Release
… Inflammatory macrophages engage bacterial endotoxins, including Gram-negative lipopolysaccharide (LPS) and Gram-positive lipoteichoic acid (LTA). And respond by releasing tumor necrosis factor-α (TNF-α). While beneficial for neutralizing acute pathogen exposure, prolonged TNF-α release …
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Human mesenchymal stromal cell regulation of pulmonary macrophage populations in the Acute Respiratory Distress Syndrome
… with hMSC-derived EVs was protective in endotoxin-induced lung injury in vivo highlighting the AM as a key cellular mediator of hMSC beneficial effects. A proportion of hMSC-EVs were found to contain mitochondria which were transferred to human macrophages in vitro facilitating hMSCs …
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Equine obesity-related hyperleptinemia
… on the endocrine and immune systems. Endotoxin was given to mares and geldings to investigate the role and/or regulation of leptin in the pro-inflammatory cytokine response. Of the endpoints measured, only platelet count differed between normal and hyperleptinemic horses. Endotoxin …
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The macrophage activating properties of growth hormone in vitro and in vivo: Comparison to interferon-gamma (IF N-gamma)
… demonstrated by showing that in vivo priming of endotoxin induced hemorrhagic necrosis of murine tumors in mice can be mediated by IFN-$\gamma$ and GH. In summary, the data presented in these experiments suggest that GH plays an important ""cytokine-like"" role in regulating M$\Phi$ functional …
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The Role of Dual Specificity Phosphatase -11 In Innate and Adaptive Immune Responses
… studies show that DUSP11 expression is induced after activation of innate and adaptive immune cells, suggesting that DUSP11 may play a role in the regulation of immune responses. To examine the function of DUSP11 in immune cells, we generated and analyzed <em>Dusp11-/-</em> mice. We …
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ASPECTS OF FLUID THERAPY: An experimental study of the effects of systemic inflammation, microvascular permeability, blood pressure and plasma volume
… systemic arterial and venous pressures. In the endotoxin induced inflammation, both activated protein C and prostacyclin reduced protein leakage in the gut and improved arterial oxygenation, and prostacyclin reduced protein leakage in the lung.
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The role of oxygen free radicals in the endotoxic shock induced myocardial dysfunction and cellular injury
… and/or scavenge OFRs, would prevent the ET-induced cardiac depression and tissue injury. To test this hypothesis experiments were carried out on anaesthetized dogs. The dogs were assigned to the following groups: (a) Sham Control, (b) Endotoxin (ET)-treated (ET-shock group), (c) …