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Showing 1 to 2 of 2 for “"Endotoxin removal"”.
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Endotoxin removal from protein solutions by immobilized metal ion affinity chromatography
In the biotechnology/pharmaceutical industry, the removal of endotoxins from final protein product has always been a challenge. A novel method for endotoxin removal from protein solutions, immobilized metal (ion) affinity chromatography (IMAC) has been developed in this study. Fe^{3+} was charged …
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Polymeric nanoparticle as a new platform for high removal of endotoxins from biopharmaceutical solutions
… gram-negative bacterial cells (<em>E.coli</em>), endotoxin present in the bacteria is released in the surrounding media thus contaminating the lifesaving biotherapeutics. Application of the endotoxin-contaminated therapeutics to humans or animals can cause serious health issues like septic shock, …