Global ETD Search

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Showing 1 to 3 of 3 for “"Endotoxin Tolerisation"”.

  1. LPS from subgingival plaque and the periodontal pathogen Porphyromonas gingivalis, its effect on M1 and M2 macrophage responses and potential as a biomarker

    … to induce a quiescent state known as endotoxin tolerance, thought to be a protective mechanism but which may also confer protective benefits to potential pathogens. Several bacteria, including keystone periopathogen Porphyromonas gingivalis (PG) is able to modify the bio-reactive …

    plymouth Repository record for LPS from subgingival plaque and the periodontal pathogen Porphyromonas gingivalis, its effect on M1 and M2 macrophage responses and potential as a biomarker (opens in a new tab)

  2. Regulation of macrophage subsets in homeostatic and inflammatory mucosal environments

    … tolerance and immune activation/inflammation. Endotoxin tolerisation (ET) is a circumstance where cells go through a hypo-responsive state, unable to respond to further endotoxin-LPS challenge. Mucosal macrophages (MΦs) have a dual functionality that determines tolerance to commensal organisms …

    plymouth Repository record for Regulation of macrophage subsets in homeostatic and inflammatory mucosal environments (opens in a new tab)

  3. Modulation of macrophage and epithelial cell immune defences by probiotic bacteria: immune stimulation versus suppression

    … of IL-10 production in the gut relate to endotoxin tolerance. Endotoxin tolerance is a context; it could present an example for cell drive through a hypo-responsive state. An example is mu-cosal inflammatory pathologies, such as Crohn’s disease. When tolerance is broken, causing the …

    plymouth Repository record for Modulation of macrophage and epithelial cell immune defences by probiotic bacteria: immune stimulation versus suppression (opens in a new tab)