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Showing 1 to 6 of 6 for “"Endothelin-System"”.

  1. Studies of the mammalian ovarian endothelin system

    In porcine ovaries, endothelin-1 (ET-1) may have an autocrine/paracrine role in follicular development. Endothelin-converting enzyme-1 (ECE-1) converts big endothelin-1 to ET-1. In situ hybridization was used to determine the ovarian compartment that synthesizes ECE-1. ECE-1 mRNA was detected in …

    wvu Repository record for Studies of the mammalian ovarian endothelin system (opens in a new tab)

  2. Endothelin system in human cardiovascular physiology and pathophysiology

    … the pharmacology and physiology of the endothelin (ET) system in human blood vessels in health, and the influence of cardiovascular disease on the ET system. This work followed from the discovery of ET-1 as a peptide endothelial mediator of vascular tone in 1988. Publications are grouped …

    edinburgh Repository record for Endothelin system in human cardiovascular physiology and pathophysiology (opens in a new tab)

  3. The structural and functional changes of blood vessels during aging

    … revealed a robust expression of endothelin system proteins in the adventitia. Additionally, extracellular matrix proteins collagen and fibronectin, and the proliferation marker Ki67 showed strong adventitial origin. The changes observed in the vascular adventitia with aging …

    brock Repository record for The structural and functional changes of blood vessels during aging (opens in a new tab)

  4. Importance of MAPK and PKC in cerebrovascular endothelin receptor changes

    Endothelin is a vasoactive peptide that exerts its effect through two receptors; the endothelin type A (ETA) and type B (ETB) receptor. The contractile ETA receptor is localized on smooth muscle cells in the vascular wall, while the ETB receptors are mainly situated on endothelial cells, mediating …

    lund Repository record for Importance of MAPK and PKC in cerebrovascular endothelin receptor changes (opens in a new tab)

  5. Proatherosklerotische Wechselwirkung von oxidativem Stress, Low-Density-Lipoprotein, Angiotensin II und Endothelin-1 in humanen Endothelzellen

    … Lipoproteinen und den blutdruckregulierenden Endothelin- und Renin-Angiotensin-Systemen untersucht. Weiterführende Analysen erfolgten an Rezeptoren für die Aufnahme von nLDL und oxLDL. Abschließend wurden Signalwege untersucht, die durch nLDL und oxLDL aktiviert werden. Tierexperimentielle …

    qucosa-diss