Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Endothelial barrier dysfunction"”.
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Signaling Induced by Inflammatory Mediators in the Rodent Pulmonary Microvasculature
… to the pathology of ALI/ARDS by increasing endothelial barrier dysfunction. Many inflammatory mediators dictate the course and gravity of the response by inducing endothelial cytoskeletal reorganization, such as induction of actin stress fibers, cell rounding and contraction, and …
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Tie-ing the endothelium: development of an mRNA-based nanotherapeutic to restore microvascular barrier function for the treatment of sepsis-induced multiple organ failure
… novel therapeutic approaches to treat sepsis. Endothelial dysfunction is a hallmark of sepsis to which the loss of Ang/Tie2 signalling, a key regulator of vascular integrity, contributes significantly, making it an attractive therapeutic target. The impairment in Tie2 pathway activity manifests …