Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Endothelial Biology"”.
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The Role of Type III Transforming Growth Factor-β Receptor in Regulating ALK1 Signaling and Endothelial Biology
… how TβRIII regulates ALK1 signaling and endothelial behavior. </p><p>Here, we establish that vascular endothelial cells express relatively high levels of TβRIII, alongside the canonical endothelium-restricted co-receptor, endoglin. Moreover, using biophysical and biochemical techniques, …
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Endothelial cell plasticity as a marker of vascular disease and predictor of adverse outcomes to stress
Endothelial cells (ECs) dynamically sense and adapt to their local biomechanical and biochemical environments, a process crucial for maintaining vascular homeostasis. Loss of this plasticity is implicated in vascular diseases, where endothelial dysfunction and maladaptive responses exacerbate …
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Investigation of the cAMP-mediated inhibitory mechanism on the signalling pathways of 2 cytokines: IL-6 and leptin in endothelial cells
… cyclic-AMP (cAMP), notably with regard to endothelial function. Many studies have shown that cAMP can limit vascular permeability by enhancing barrier function and reducing pro-inflammatory effects of cytokines. Although the protective effects of cAMP elevation on limiting endothelial …
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An Optogenetic Toolbox for the Interrogation of Dynamic Events During Angiogenesis
… LightR-VEGFR2 regulation was perturbed in endothelial cells. These findings highlight the challenges in the creation of LightR-RTKs but also provide a logical foundation for their creation. Another immediate consequence of angiogenic stimulation is rapid alteration of the endothelial …