Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Endosomal recycling pathway"”.
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Inhibition of the endosomal recycling pathway to overcome resistance to cancer therapies
… lab and others have found that inhibition of the endosomal recycling pathway may be a promising strategy to downregulate clinically relevant cell surface proteins and to overcome drug resistance. This thesis focuses on two clinically relevant hormone receptors that are strongly linked to the …
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Dynamics of Alpha5 Integrin, Paxillin, and Alpha-Actinin During Formation and Disassembly of Adhesions in Migratory Cells
… These vesicles co-localize with markers for endosomal recycling pathway, including the dye FM 4-64 and transferrin receptor staining. Paxillin organizes into dynamic complexes in areas of membrane activity and paxillin from older complexes dissipates in close temporal coordination with the …
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Impact of endosomal recycling inhibitors on drug resistant and immune tolerant breast cancers
… transporters, and the potential repurposing of endosomal recycling inhibitors (ERIs) to target these drug-tolerant cells. Additionally, we examined the effects of ERIs on the total protein and surface levels of immune checkpoint proteins. This was done by targeting the recycling of the …