Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Endogenous cannabinoids"”.
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Ghrelin, Cannabinoids, and Motivation: Increased Food Motivation on Progressive Ratio Paradigm Through MAGL/FAAH Inhibition in a Rat Model
Both ghrelin and endogenous cannabinoids act in the ventral tegmental area (VTA) to increase feeding behaviours, through their interaction is not understood. It is hypothesized that ghrelin influences this system by stimulating the release of endocannabinoids from dopamine cells through its …
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Targeting the Endocannabinoid System to Reduce Inflammatory Pain
<p>The endogenous cannabinoids (endocannabinoids) anandamide (AEA) and 2-arachidonylglycerol (2-AG) exert their effects predominantly through cannabinoid CB1 and CB2 receptors, but these actions are short-lived because of rapid hydrolysis by fatty acid amide hydrolase (FAAH) and monoacylglycerol …
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Cannabinoid Modulation of Chemotaxis of Macrophages and Macrophage-like Cells
Exogenous and endogenous cannabinoids have been reported to modulate functional activities of macrophages. It is recognized that macrophages express primarily the CB2 cannabinoid receptor, but recent studies indicate that its expression is differential in relation to activation state with maximal …
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The Developmental and Behavioral Effects of Δ9-Tetrahydrocannabinol on a Spastic Mutant
… with GABA-agonistic benzodiazepines. Exogenous cannabinoids also modulate GABAergic signaling, and THC, one of the natural compounds that prompted the discovery of the endocannabinoid system mimics the effects of endogenous cannabinoids at endocannabinoid and non-cannabinoid sites in the central …
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Effects of acute and repeated cannabinoid injections on immediate and delayed object memory and unconditioned anxiety – a developmental trajectory
… G-protein coupled receptors (GPCRs) that bind endogenous and exogenous cannabinoids. In an unaltered state, endogenous cannabinoids regulate system function and synchrony. Administration of cannabinoids such as Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD), which are found in the cannabis …
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Molecular Biophysics of Mammalian and Fungal Macromolecular Assemblies
<p>Nuclear Magnetic Resonance Spectroscopy (NMR) is a powerful and highly versatile analytical tool that allows for the collection of data reflecting the macromolecular organization of an ordered structure, and even intramolecular interactions of nuclei. This thesis details two projects that …