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Showing 1 to 20 of 104 for “"Endoderm"”.

  1. Human Embryonic Stem Cells - Constitutive Gene Expression and Differentiation Towards Definitive Endoderm and Posterior Foregut Endoderm

    Norrman, KarinStem Cells and Pancreas Developmental Biology, Dept of Laboratory Medicine2011

    … research tools. Identification of definitive endoderm (DE) - from where pancreas originates, requires analysis methods that can detect multiple markers within individual cells, since many markers expressed in DE are also detected in extraembryonic endoderm. In this thesis, we approached single …

    lund Repository record

  2. Regeneration of Hydra From the Enzymatically Isolated Endoderm

    Normandin, Diane KilbourneUniversity of Illinois at Urbana-Champaign2014

    Made available in DSpace on 2014-12-04T22:46:17Z (GMT). No. of bitstreams: 1 6206199.pdf: 3542892 bytes, checksum: e66da1eea58e55e7c3ca54feeee19e06 (MD5) Previous issue date: 1962

    uiuc Repository record

  3. FGF signaling in specification of hESC-derived definitive endoderm

    Ameri, JacquelineStem Cells and Pancreas Development Biology2010

    … Pancreas originates from the definitive endoderm (DE), one of the three germ layers. The path from definitive endoderm to pancreatic progenitor cells and finally the insulin producing beta cells involves sequential cell-fate decisions characterized by the expression of multiple …

    lund Repository record

  4. Spatial Analysis of Liver Bud, Heterogeneity in Endoderm Induction, Silencing Effect of Foxa1/2 in HepG2 Cells

    Mon, Tala; 0000-0003-4341-2120State University of New York at Buffalo2019

    M.S.

    buffalo Repository record

  5. The role of pou2/spiel-ohne-grenzen (spg) in brain and endoderm development of the zebrafish, Danio rerio

    Reim, GerlindeTechnische Universität Dresden

    … that pou2 is a key factor controlling endoderm differentiation. By expression and gain-of-function analysis I suggest a cell autonomous function for Pou2 in the first step of endodermal differentiation. By gain-of-function experiments involving the gene encoding the HMG transcription …

    qucosa-diss

  6. Development of an Interferon Bioassay and Primitive Endoderm Cell Lines to Study Lineage Specification During Early Bovine Embryogenesis

    Mccoski, Sarah R.Virginia Tech2015

    … events, trophectoderm (TE) and primitive endoderm (PrE) specification, occurring between days 6 and 8 of gestation. The TE is responsible for uterine attachment and production of interferon-tau (IFNT), the factor of maternal recognition of pregnancy in ruminants. The PrE forms the yolk …

    vt Repository record

  7. Endodermal Patterning in Xenopus laevis

    Benites da Costa, RicardoUniversity of Cambridge2004

    The endoderm is the inner germ layer of the vertebrate embryo from which the respiratory and digestive systems are derived. These include organs such as the liver, pancreas, stomach, lungs and intestine. Recent research has helped our understanding of early vertebrate endoderm specification and …

    cambridge Repository record

  8. Mechanisms of Foregut Formation in Mus Musculus

    Kretzschmar, JennyUniversity of Cambridge2025

    … forms by the invagination of the anterior endoderm at embryonic day 7.5 and later gives rise to essential organs of the gastrointestinal and respiratory system. The formation of the foregut is critical for establishing the anterior organisation of the embryo, including the positioning of …

    cambridge Repository record

  9. EXPERIMENTAL DISENGAGEMENT OF MORPHOGENETIC PROCESSES AND ITS EFFECTS ON PRIMORDIAL GERM CELL COLONIZATION OF THE GONADAL RIDGES IN RANA PIPIENS

    PENKALA, JOSEPH EDWARDRice University1986

    … a displacement from deep within the ventral endoderm of the Stage 17 tailbud embryo to the dorsal endodermal crest of the hatched Stage 20 larva; eventually they exit the endoderm and populate the paired gonadal primordia. This study examines the migratory properties of PGCs and the …

    rice Repository record

  10. Directed differentiation of endodermal cells from mouse embryonic stem cells

    Kim, Peter Tae WanUniversity of British Columbia2008

    … an attempt has been made to produce definitive endoderm and subsequently cells that can serve as pancreatic and hepatocyte precursors from mouse embryonic stem cells. By using retinoic acid and basic-FGF, in the absence of embryoid body formation, mouse embryonic stem cells were differentiated …

    ubc Repository record

  11. A Study of Mouse Peri-Implantation Morphogenesis

    Weberling, AntoniaUniversity of Cambridge2022

    … lineages, the trophectoderm and primitive endoderm. My first goal was to characterise the blastocyst to egg cylinder transition in mouse embryos and understand its mechanism through live imaging and inhibitor treatments (1). Then, I aimed to examine how the interplay between the polar …

    cambridge Repository record

  12. SMAD2/3 - FOXH1 regulation during cell cycle progression upon differentiation

    Perrin, MarionUniversity of Cambridge2022

    … mediated by nocodazole with our well-established endoderm differentiation protocol to study the coordination between cell cycle and differentiation. This approach first revealed that the transition from pluripotency to definitive endoderm requires two cell cycles. I then focused on the forkhead …

    cambridge Repository record

  13. The role of transcription factor GATA6 in the development of the human pancreas

    Chia, Crystal YingUniversity of Cambridge2018

    … is required for the formation of the definitive endoderm (DE) and pancreas in humans; hPSCs harbouring homozygous GATA6 mutations fail to form the definitive endoderm, and consequently the pancreas, whereas hPSCs harbouring heterozygous GATA6 mutations exhibited impairment in definitive endoderm …

    cambridge Repository record

  14. Manipulating Embryonic Development and Endometrial Function in Ruminants

    McCoski, Sarah R.Virginia Tech2018

    … lineages. One such lineage is the primitive endoderm, which will eventually give rise to the yolk sac. Once believed to be a vestigial structure, the yolk sac is now believed to play a more prominent role in embryogenesis as it provides nutrients to the preimplantation embryo. The endoderm …

    vt Repository record

  15. Enforced Expression of Tbx1 In Fetal Thymic Epithelial Cells Antagonizes Thymus Organogenesis

    Cardenas, Kim T2011

    … domains of 3rd pharyngeal pouch (PP) endoderm. At embryonic day 11.5 (E11.5), the ventral thymus and dorsal parathyroid domains can be identified by <em>Foxn1</em> and <em>Gcm2</em> expression respectively. Neural crest cells, (NCCs) play a role in regulating patterning of 3rd PP …

    uthsc Repository record

  16. The evolution and function of pharyngeal arch signalling centres in jawed vertebrates

    Rees, JenaidUniversity of Cambridge2022

    … of tissue that form when pouches of foregut endoderm contact surface ectoderm on either side of the embryonic vertebrate head. In fishes, endodermal pouches fuse with surface ectoderm to form gill slits. Once delineated, pharyngeal arches undergo morphogenesis and differentiation, giving rise …

    cambridge Repository record

  17. Hyperosmotic Stress Enzyme Signaling Modulates Oct4, Nanog, And Rex1 Expression And Induces Prioritized Differentiation Of Murine Embryonic Stem Cells

    Slater, Jill A.2013

    … upregulating</p> <p>markers of primitive endoderm and suppressing epiblast markers.</p> <p>The studies were continued in the peri-implantation model, embryoid bodies</p> <p>(EBs), in which differentiation is allowed rather than actively suppressed. Unstressed</p> <p>EB culture …

    wayne-thes Repository record

  18. An in vitro model of human yolk sac and epiblast crosstalk

    Mackinlay, KirstyUniversity of Cambridge2022

    … Within mouse development, the anterior visceral endoderm (AVE), formed from the extraembryonic endoderm, plays a crucial role in restricting primitive streak formation to the posterior epiblast, thereby establishing the anterior-posterior axis of the mouse embryo. Recent studies of human embryos …

    cambridge Repository record

  19. Gene expression studies of pregastrulation development: the basement membrane is essential for cell differentiation

    Åkerlund, MikaelDepartment of Experimental Medical Science, Lund Univeristy2009

    … is initiated with the formation of an endoderm. A subendodermal BM is formed, in which the globular domains LG4-5 of the laminin α1 chain (α1LG4-5) are responsible for the induction of the epiblast EBs derived form embryonic stem (ES) cells, modified to repress FGF receptor signaling, …

    lund Repository record

  20. Anteriore Musterbildung im Wirbeltierembryo - Die Induktion von Vorderhirn und Herz

    Wittler, Lars2012

    … auf Signalen aus dem anterioren, primitiven Endoderm. Dennoch sind, wie in dieser Arbeit gezeigt werden konnte, Signale aus der Spitze des Primitivstreifens ausreichend und notwendig, um eine stabile Vorderhirnidentität zu etablieren. Die Ergebnisse erlaubten eine Neubewertung der Hypothese …

    goettingen Repository record

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