Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"Endocrine Therapy Resistance"”.
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Proteomic Investigation of Endocrine Therapy Resistance in Breast Cancer Investigating the Molecular Mechanisms for SERM Resistant Cell Lines Using SILAC-Based Proteomic Approach
… of cancer mortality in women worldwide. Hormonal therapy is considered one of the most effective therapies and is used against luminal-type malignancies. However, 40-50% of tumour cells can develop resistance, thereby limiting the success in breast cancer treatment. In this study, mechanisms of …
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The role of human DEAD-box protein DDX3X in the activation and function of Estrogen Receptor-alpha
… manner, leading to cell proliferation and resistance to anti-estrogen treatment. The current study aimed to investigate whether DDX3 and IKKɛ also collaborate in the activation of ERα. This work suggests that DDX3 and IKKɛ collaborate to mediate ERα phosphorylation and activation, akin to …
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Impact of metabolic pathways on ER+ metastatic breast cancer therapy response
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2026-12-01