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Showing 1 to 6 of 6 for “"Enamides"”.

  1. A Diversity-Oriented Synthesis Approach to Functionalized Azaheterocycles using Cyclic Alpha-Halo Eneformamides

    … through the intermediacy of α-halo enamines/enamides. The synthetic utility of the method is exemplified through the construction of quaternary cyclic propargylic and homoallylic amines, polycyclic lactams, as well as chiral dihydro 1,4-oxazines and thiazines. Given the generality of the …

    central-wash Repository record for A Diversity-Oriented Synthesis Approach to Functionalized Azaheterocycles using Cyclic Alpha-Halo Eneformamides (opens in a new tab)

  2. Utilising Non-Covalent Interactions in Developing Enantioselective Radical Transformations

    … acceptors, in the form of electron-rich enamides, is disclosed. While high enantioselectivities were achieved in some cases, the reaction was found to be effective only for a limited range of substrates. Thirdly, the Minisci-type addition of cyclic α-amino radicals into heteroarenes is …

    cambridge Repository record for Utilising Non-Covalent Interactions in Developing Enantioselective Radical Transformations (opens in a new tab)

  3. Metal-Catalyzed Formation and Transformations of Carbon-Boron Bonds

    … enoates and primary, secondary, and tertiary enamides under very mild conditions. As an inexpensive and earth abundant metal, catalysts based on copper are highly desirable. An international collaborative project to develop a copper-catalyzed cross-coupling reaction of beta-boryl carbonyl …

    vt Repository record for Metal-Catalyzed Formation and Transformations of Carbon-Boron Bonds (opens in a new tab)

  4. Advances in Heterocyclic Synthesis through Ring Expansions and Flow Chemistry

    … to form substituted imines, enamides, and amines. This new variation of the Schmidt reaction provided access to unique heterocycles. Enabling Chemistry Technologies: High-Temperature and High-Pressure Continuous Flow Chemistry. The synthetic applications of a high-temperature …

    ku Repository record for Advances in Heterocyclic Synthesis through Ring Expansions and Flow Chemistry (opens in a new tab)

  5. Development of Novel Methods for the Installation of Trifluoromethyl/Boryl and 1,2,4-Oxadiazole Moieties

    … into the trifluoromethyl group to afford β-CF3 enamides. 31P NMR studies were conducted to elucidate the mechanism. Finally, chapter 5 provides insight into the synthesis of 1,2,4-Oxadiazoles which are privileged scaffolds in medicinal chemistry. The developed reaction occurs under metal-free …

    vt Repository record for Development of Novel Methods for the Installation of Trifluoromethyl/Boryl and 1,2,4-Oxadiazole Moieties (opens in a new tab)