Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 60 for “"Ena"”.
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Characterization of Tuba, a novel Ena/VASP ligand, and function of Ena/VASP proteins in mouse development
… cells movement, adhesion and shape change. The EnaNASP family of proteins controls actin filament elongation and are important regulators of axon guidance and cell motility. In vertebrates, the family consists of Mena (Mammalian Enabled), VASP (Vasodilator Stimulated Phosphoprotein), and EVL …
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Ena/VASP proteins regulate vertebrate nervous system development : a thesis presented
… upon regulation of the actin cytoskeleton. Ena/VASP proteins are able to remodel the actin cytoskeleton in response to extracellular signals and have been shown to regulate the motility and morphology of a variety of cells. I have investigated the in vivo requirement for the vertebrate …
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Repulsive axonal pathfinding requires the Ena/VASP family of actin regulatory proteins in vertebrates
… genetically deficient for all three vertebrate Ena/VASP homologues: Mena, VASP, and EVL. As has been reported previously in invertebrates, these defects share phenotypic overlap with those seen in mice genetically deficient for the repulsive guidance molecules Slit and Robo. I find that the …
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The role of Ena/VASP and associated proteins in regulation of neuronal morphology and filopodia architecture
… remodeling remain poorly understood. The Ena/VASP family of proteins function as key signaling molecules that influences actin reorganization in response to environmental cues, and has been implicated in many aspects of development. My work has focused on defining the mechanisms by which …
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A lentiviral system for RNAi transgenesis and the Ena/VASP triple-knockout defines neuronal and non-neuronal functions in mouse development
… signaling pathways remains unclear. The Ena/VASP protein family is a common downstream effector of multiple axon guidance signaling cascades. The analysis of the Ena/VASP triple-null mouse allows us to determine the extent to which these intracellular cascades have been conserved in the …
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Resilience Engineering via Bifurcation and Ecological Network Analysis: Demonstrated in an Electric Power Case Study
… of new technologies and actors into the network, enables reliable operation but introduces vulnerabilities to unexpected and varied disruptions and cascading failures, making resilience a critical concern. Traditional risk management and resilience assessment methods often struggle with the …
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Toca-1 driven actin polymerisation at membranes
… cells send out dynamic actin protrusions that enable them to sense and interact with their environment, as well as generating physical forces. Linking of the actin cytoskeleton to the cell membrane is essential for the formation of these protrusions. The proteins that are thought to fulfil such …
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Analysis of signal transduction pathways and the cytoskeleton in VASP-deficient cell lines and mouse models
… (VASP) is a founding member of the Ena/VASP family of proteins that includes Drosophila Enabled (ena), the mammalian Ena homologue (Mena) and the Ena-VASP-like protein (Evl). VASP was initially discovered and characterized as a substrate for cGMP- and cAMP-dependent protein kinases …
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Perfil de recuento de leucocitos, vhs y de anticuerpos fr, ana y ena de pacientes con parotiditis cronica recurrente infantil atendidos en el hospital san juan de dios
… VHS, y exámenes inmunológicos: FR, ANA y ENA, en ausencia de xerostomía y xeroftalmia. El presente estudio busca investigar la relación entre la PCRI y el SSI mediante el análisis del perfil de exámenes de laboratorio de pacientes con PCRI: recuento de leucocitos, VHS y exámenes …
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How short, degenerate motifs across the human proteome recognize the actin remodeling factor ENAH
… SLiMs in modulating binding to the SLiM-binding Ena/VASP EVH1 domain family. I identified three mechanisms by which adjacent and distal sequence elements surrounding native EVH1-binding SLiMs enhance binding affinity and specificity to ENAH, an Ena/VASP paralog. I also determined the strategies …
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Elaboration of the Homer1 Recognition Landscape Reveals Incomplete Divergence of Paralogous EVH1 Domains
… the motif of a related EVH1 domain from the Ena/VASP family of actin regulatory proteins. An analysis of EVH1 binding preferences in distantly related orthologs suggests that this overlapping preference originated in the ancestral domain that gave rise to distinct Ena/VASP and Homer protein …
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Immigration, ethnicity and national identity : Maghrebis' socio-political mobilisation and discourse in the inter-war period and during the 1970s in France
… The first one, the Etoile nord-africaine (ENA), later to become the Parti du peuple algerien (PPA), developed during the inter-war period and became the strongest voice of Algerian nationalism during those years. The second one, the Mouvement des travailleurs arabes (MTA), which was created …
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Job satisfaction of emergency nurses in Tennessee
… organization, The Emergency Nurses Association (ENA) and those who do not. The sample of 458 nurses consisted of two groups. Group I were ENA members (n = 239). Group II was composed of emergency nurses who were not ENA members (n = 219). Herzberg's two-factor theory was used in the descriptive …
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Functional traits and resource-use strategies of native and invasive plants in Eastern North American forests
… and liana species in Eastern North American (ENA) forests to test the overarching hypothesis that non-native understory species invasive to this region have superior resource-use strategies, or alternatively, they share the same metabolic tradeoffs as the native flora. First, at a global …
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Estudio de factibilidad para la producción y comercialización de bebidas biofortificadas a partir de maíz y sorgo
… alianza con la Escuela Nacional de Agricultura (ENA), se desarrolló el presente estudio de factibilidad para la producción y comercialización de bebidas biofortificadas a partir de estos granos. El estudio profundiza aspectos como: Estudio de mercado, estudio técnico, estudio económico-financiero …
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The 5' inositol phosphatase SHIP2 regulates EGF-elicited protrusion in MTLn3 cells
… lymphatic system, and colonize a distant organ. Mena, a member of the Ena/VASP family of proteins, is upregulated in invasive populations of breast cancer cells. The Ena/VASP (enabled/vasodilator-stimulated phosphoprotein) family of proteins regulate both the geometry and dynamics of actin …
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Ion Temperatures in Earth's Inner Magnetosphere: Ring Current Dynamics, Transient Effects, and Data-Model Comparisons
… from remotely imaged energetic neutral atom (ENA) measurements. The high-speed-stream-driven event on 22 July 2009 and the coronal mass ejection-driven event on 30-31 October 2013 are simulated and compared against identical simulations using a statistically derived boundary condition …
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Geology and Tectonic Significance of the Late Precambrian Eastern Blue Ridge Cover Sequence in Central Virginia
… rift basalts-diabases of eastern North America (ENA). The ENA samples, as well as the post Grenville mafic rocks in the Blue Ridge, tend to plot outside the within-plate field. It is clear that geochemical data alone may give a wrong tectonic classification, and that a knowledge of field …
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Eignung von Mikrokosmen zur Bewertung von Selbstreinigungsprozessen (Natural Attenuation) im Grundwasser eines ehemaligen Kokereigeländes
… um Möglichkeiten der Abbausteigerung (ENA-Maßnahmen) zu untersuchen. Zudem wurden verschiedene Aspekte des Mikrokosmendesigns bewertet. Insgesamt stellten Mikrokosmen ein wertvolles und vielseitiges Instrument für die Bewertung von Selbstreinigungs-Prozessen im Aquifer dar.
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Availability and cost of capital for IPP wind energy project financing in South Africa : an investigation study into how financiers and investors in the South African wind power market react to perceived uncertainties in the policy and regulatory ena
… based off the uncertainty due to the gaps in the enabling environment.
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