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Analysis of Nanopore Detector Measurements using Machine Learning Methods, with Application to Single-Molecule Kinetics

Landry, Matthew

At its core, a nanopore detector has a nanometer-scale biological membrane across which a voltage is applied. The voltage draws a DNA molecule into an á-hemolysin channel in the membrane. Consequently, a distinctive channel current blockade signal is created as the molecule flexes and interacts …

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