Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"Embryotoxicity"”.
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Embryotoxicity of dioxin-like chemicals extracted from American eels (Anguilla rostrata) from the St. Lawrence River System
… in Lake Ontario are toxic to fish embryos, and embryotoxicity is expressed as a series of malformations known as blue sac disease (BSD). I assessed whether these toxicants are in high enough concentrations in sexually maturing, eels to be embryotoxic to their offspring, as assessed by using …
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Embryo and Gamete Development Upon Exposure to CCA Components: CrO3, CuO, and AS2O5
… two-cell embryo assay was proposed to detect embryotoxicity of the CCA components and their mixtures. Total blastocyst cell numbers, analyzed by fluorescent DNA-binding, were the indicator of embryotoxicity on the subcellular level. Oocytes, in vitro-matured in the presence of CCA components, …
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Screening of radioprotective agents using zebrafish and Therapeutic effects and protective mechanism of radioprotective candidates on radiation-induced oral mucositis
… effects. KRG attenuated the radiation-induced embryotoxicity in the zebrafish model. Irradiation of HaCaT cells caused apoptosis and changed in mitochondrial membrane potential (MMP). KRG inhibited the radiation-induced apoptosis and intracellular generation of reactive oxygen species (ROS), …
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Novel Synthetic Compound, KR-22332, has radio-protective effect through inhibition of Mitochondrial Dysfunction and ROS Generation
… to apoptosis were investigated. Then, the embryotoxicity of KR-22332 were explored in a zebrafish model. Radiation-induced apoptosis and altered mitochondrial membrane potential in primary human keratinocyte (HaCaT) was observed. KR-22332 inhibited radiation-induced apoptosis and …
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Zebrafish cardiovascular cDNA microarrays : expression profiling and gene discovery in embryos exposed to 2,3,7,8-Tetrachlorodibenzo-ρ-dioxin
… However, the mechanism of TCDD cardiovascular embryotoxicity is poorly understood. The primary goal of this thesis was to identify TCDD-responsive genes likely to be involved in processes of toxicity. We constructed microarrays using cDNA libraries derived from zebrafish embryonic and adult …
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A study of acetylcholinesterase and cholinesterase in the fetal mouse brain and a study of the effects of three teratogens, vitamin A, cyclophosphamide and sodium valproate on the fetal mouse central nervous system
… of these techniques in the prediction of the embryotoxicity of drugs, and progress in the understanding of underlying mechanisms are discussed.
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Combined effects of bioavailable organic contaminants in the aquatic environment.
In contrast to conventional spot or bottle water sampling techniques, passive sampling has been shown to be a reliable and efficient method for monitoring the toxicologically-relevant, freely-dissolved (e.g. bioavaialable) concentrations of a wide range of organic contaminants in water. At the same …