Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Embryonic Disc"”.
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Spatial Transcriptome Profiling of Gastrulating Primate Embryos
… development, the pluripotent cells of the embryonic disc, the embryo proper, undergo gastrulation. This key process establishes the three germ layers, endoderm, mesoderm and ectoderm, which set the basis for all tissues emerging in the human embryo. Since postimplantation human embryos …
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NOGGIN Transport in a Model Human Epiblast
… within our model of the polarized human embryonic disc. Here, I report the surprising discovery that in human epiblasts, NOGGIN and BMP4 were selectively secreted into opposite sides of the polarized epithelium, effectively segregating the ligand and its inhibitor into distinct …
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Investigating the Actions of Interleukin-6 Family Members on Post-Hatching Blastocyst Development in Cattle
… Specifically, cell allocations within the bovine embryonic disc (ED) were investigated. Supplementing IL6 from d 5-12 increased epiblast (EPI) cell number, reduced hypoblast (HYPO) presence, and increased the EPI:HYPO ratio in d 12 blastocysts. These IL6 effects could not be replicated when IL6 …
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Pluripotency and patterning in nonhuman primate embryogenesis
… epiblast, and (2) primed pluripotency in the embryonic disc (EmDisc) in the context of anterior-posterior axis patterning. First, imaging and virtual reconstruction of implanted marmoset embryos generated genome-wide, 3D expression patterns before and after primitive streak formation. Spatial …
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Genesis of the human germline
… analysis with existing human and primate embryonic datasets demonstrates that our model represents the lineages at the caudal region of the embryo, including mesoderm, endoderm, PGCs and amnion. I found a high degree of fidelity between in vitro PGCLC and bona fide early embryonic PGCs, …