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Showing 1 to 3 of 3 for “"Elexacaftor–Tezacaftor–Ivacaftor"”.

  1. An investigation of the cellular effects of novel agents and multi-drug combinations in cystic fibrosis

    … azithromycin (AZ). Given the emergence of elexacaftor/tezacaftor/ivacaftor (ETI), which is expected to restore CFTR activity in 90% of the CF population. The aim of this part of the study was to examine the effect of AZ and ETI, singly and in combination, to assess potential …

    qu-belfast Repository record for An investigation of the cellular effects of novel agents and multi-drug combinations in cystic fibrosis (opens in a new tab)

  2. Cystic fibrosis in South Africa: spectrum of disease, diagnosis, and determinants of outcome

    … one copy of F508del and are, thus, eligible for elexacaftor/tezacaftor/ivacaftor. A key finding of the registry-based studies was that lung function and nutrition outcomes in SA were significantly lower across all ages compared with Canada, attributed to differences in the quality of CF care and …

    cape-town Repository record for Cystic fibrosis in South Africa: spectrum of disease, diagnosis, and determinants of outcome (opens in a new tab)