Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Electrostatic binding,"”.
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Optimization of electrostatic binding free energy : application to barnase and barstar
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Physics, 1999.
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Optimization of electrostatic binding free energy : applications to the analysis and design of ligand binding in protein complexes
Electrostatic interactions play an important role in determining the energetics of association in biomolecular complexes. Previous work has shown that, within a continuum electrostatic model, for any given complex there exists a ligand charge distribution which optimizes the electrostatic binding …
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Polyelectrolyte multilayers incorporating photocrosslinking polymers for controlling 2- and 3-dimensional structure
… these polymers in the film and their resultant binding state. Patterning covalent binding through photo-crosslinking in addition to electrostatic binding, can locally override the native tendency to change structure with changes in pH. To achieve this, poly(acrylic acid) was chemically modified …
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Synthesis and Characterization of Nucleobase-Containing Polyelectrolytes for Gene Delivery
… precedence exists for polymers containing electrostatic interactions and polymers containing hydrogen bonding motifs, however the combination of electrostatic and hydrogen bonding interactions is not widely investigated in current literature. Polyelectrolytes containing hydrogen bonding …
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Genetically engineered phage fibers and coatings for antibacterial applications
… bacteriophage (or phage) enables solution-based, electrostatic binding of silver ions and subsequent reduction to metallic silver along the phage length. Antibacterial fibers of micrometer-scale diameters are constructed from such E3-modified phage, via wet-spinning and glutaraldehyde-crosslinking …
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Identification of esters in carious dentine Staining and chemo-mechanical excavation
… The latter aimed to evaluate the type of binding, electrostatic or covalent, to carious dentine. In a systematic review with an adjacent meta-analysis, the ability of a chemically based product in clinical caries excavation was evaluated by comparing the efficacy of chemo-mechanical …
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Method Development And Applications To Screening And Characterization Of Rrna-Targeting Small Molecules
… ring aminoglycoside analogues was tested for binding to a model RNA representing the A site using electrospray ionization mass spectrometry (ESI-MS). Several of the synthetic analogues with low molecular weights were found to bind to the RNA with affinities comparable to the parental …
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Development of Dendritic Polymers as a Modular Drug Delivery Platform for Avascular Tissues
… cationic nanocarriers have been studied to electrostatically bind to avascular tissues and deliver therapeutics for extended periods. Recently, cationic poly(amido amine) dendrimers partially modified with poly(ethylene glycol) chains (PEG-PAMAM conjugates) have shown promise in …
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Eco-Friendly Chemical Herders For Remediation Of Maritime Oil Spill
… of marine organisms in the layer, and upon binding to the herding monolayer can form more durable layers with potentially large dilatational viscosity. A representative negatively charge polysaccharide present in the microlayer, λ carrageenan, is used. Surface pressure measurements show that …