Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 38 for “"Electrospray Ionisation"”.
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An investigation of beryllium coordination chemistry using electrospray ionisation mass spectrometry
The electrospray ionisation mass spectrometric behaviour of various complexes of beryllium have been investigated in this thesis. These beryllium complexes were prepared in situ on a small scale by preparing appropriate molar mixtures of the Be²⁺ ion with ligands in a range of solvent systems. In …
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Mathematical modelling of unsteady tube stretching with internal channel pressurisation for fabricating electrospray ionisation emitters
Nanoelectrospray ionisation (nESI) is a useful technology for assessing the chemical composition of various liquid samples using mass spectrometry (MS). Signi cant e orts have been made in the design of nESI emitters, as their shape and geometry are critical to the electrospray performance and …
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The Characterisation of Oilfield Chemicals by Electrospray Ionization Multi-Stage Mass Spectrometry (ESI-MSᵑ)
… In the present study, the use of multistage electrospray ionisation ion trap mass spectrometry (ES1-MSᶯ) was investigated for the detection, identification, characterisation and quantification of compounds in both speciality oilfield chemicals (corrosion inhibitors, scale inhibitors, biocides …
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The off-line and on-line analysis of liquid process streams by mass spectrometry
… mass spectrometry and atmospheric pressure ionisation-mass spectrometry.The technique of total vaporisation analysis completely vaporises liquid samples in a gas chromatograph heated injection inlet and analyses the vapour created with a mass spectrometer. Headspace analysis and membrane …
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The effect of eicosapentaenoic acid on brain and platelet produced bioactive lipid mediators. The effect of eicosapentaenoic acid, docosapentaenoic acid and other polyunsaturated fatty acids on the eicosanoids and endocannabinoids produced by rat brain and human platelets using electrospray ionisation tandem mass spectrometry-based analysis.
Eicosapentaenoic acid (EPA) is a polyunsaturated fatty acid (PUFA) with neuroprotective and cardioprotective properties. It is thought that some of the actions of EPA may be attributed to its elongated metabolite, the PUFA docosapentaenoic acid (DPA). Docosahexaenoic acid (DHA) and arachidonic acid …
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Development and Construction of a new Photoelectron Imaging Spectrometer for Studying the Spectroscopy and Ultrafast Dynamics of Molecular Anions
… gas phase. The new instrument incorporates: an electrospray ionisation source, which is capable of generating a vast class of molecular anions; a Wiley-McLaren time-of-flight mass spectrometer; and a compact photoelectron imaging arrangement for anions, which negates the use of pulsed high …
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The use of model compounds to investigate the influence of fuel composition on the thermo-oxidative stability of fame/diesel blends
… (GC) with mass spectrometric (MS) and flame ionisation (FID) detection. Further analytical methods included Fourier transform infrared (FTIR) and ultraviolet-visible (UV-Vis) spectroscopy as well as electrospray ionisation-mass spectrometry (ESI-MS).
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A quantitative characterisation of phospholipid composition and biosynthesis in HeLa cells and nuclei - a mass spectrometry study
… as transcription. This study utilised tandem electrospray ionisation mass spectrometry to determine, quantitatively, the phospholipid content of cultured HeLa (Human cervical carcinoma) cells and their isolated naked nuclei. Endonuclear PC, DAG and PI was found to be enriched in disaturated …
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Ion mobility and mass spectrometric investigations of organophosphates related to chemical warfare agents and pesticides
… monomer and ammoniated dimer ions. Using an ElectroSpray Ionisation (ESI) - ITMS, the fragmentation pathway of dimethyl ethylphosphonate (DMEP) is investigated. The isotopomers of DMEP have unusual fragmentations, and density functional theory calculations are used to aid in the …
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The Photodegradation of Diazepam and its Human Metabolites in Water
… liquid chromatography (HPLC) separation with electrospray ionisation multistage mass spectrometry (ESI-MS") detection. Results demonstrated that whilst the compounds were hydrolytically stable in aqueous solutions, photolysis significantly reduced the concentration of diazepam and its …
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The Development of High Accuracy Methods for the Measurement of Metal Speciation
… coupled plasma mass spectrometry (ICP-MS) and electrospray ionisation mass spectrometry (ESI-MS). The spike was shown to be stable. An oyster metallothionein (MT) was also produced using recombinant techniques. Methylmercury (MeHg) was determined in an International Measurement Evaluation …
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Biosynthesis and characterisation of polyhydroxyalkanoate biopolymers and their oligomers for circular economy
… from the [text redacted] starting material. Electrospray ionisation mass spectrometry (ESI-MS) confirmed the monomer composition of the polymer produced with LDPE and PE-T to be 3-hydroxybutyrate, 3-hydroxyvalerate and 3-hydroxyhexanoate and that with [text redacted] to be 3-hydroxybutyrate …
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Studies of UHPLC-MS performance and application to rapid sensitive and robust drug analysis
… phase composition and pH on efficient and stable ionisation are studied for robust and sensitive analysis of basic analytes. Different mobile phase conditions are evaluated with electrospray ionisation (ESI) and atmospheric pressure chemical ionisation (APCI), with high pH eluents generating …
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Analysis of carbonaceous solid deposits from thermal stressing of FAMEs and FAME/diesel blends at different temperatures in a continuous flow reactor
… ultraviolet visible spectroscopy (UV-Vis) and electrospray ionisation-mass spectroscopy (ESI-MS) in order to provide further insight into the chemical processes preceding deposit formation. The test fuels stressed in this study were an EN 590 reference diesel and two fatty acid methyl esters …
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Sviluppo di tecniche di analisi ifenate per la quantificazione di biomarcatori di esposizione a tossici ambientali: gli acidi mercapturici
… analysed with a liquid chromatography coupled to electrospray ionisation-mass spectrometry (μHPLC-ESI-MS/MS) method for the simultaneous quantitative detection of the BTX exposure biomarker SPMA, SBMA and o-MBMA in human urine. Urinary S-phenylmercapturic acid (SPMA) is a biomarker proposed by the …
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The bacterial synthesis and characterisation of polyhydroxyalkanoates using waste plastics as carbon sources for novel applications
… included nuclear magnetic resonance (NMR) and electrospray ionisation tandem mass spectrometry (ESI-MS/MS). It can be concluded, that oxidised PE (O-PEW), non-oxidised PE (N-PEW), thermally treated PP and PS could be promising carbon sources for PHA production in the future. In terms of PHA …
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The influence of the hormonal milieu on eicosanoid and cytokine production in tissues from the female reproductive tract.
… (n=7)) by liquid chromatography coupled with electrospray ionisation mass spectrometry (LC/ESIMS/ MS). Cytokines produced by CVF collected from pregnant donors (20-41 weeks gestation, n=2-10) were investigated using Enzyme-Linked Immunosorbent Assay (ELISA) or Luminex®. Human endometrium …
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Development of copper peptide complexes as anti-Inflammatory drugs
… (Uv-Vis), nuclear magnetic resonance (NMR), electrospray ionisation mass spectrometry (ESI-MS) spectroscopy as well as molecular mechanics (MM) calculations. The visible spectra obtained for the different species in solution were typical of Cu(II) and Ni(II) complexes. 1H NMR identified the …
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The identification of prostate cancer associated tumour antigens and biomarkers
… coupled to Matrix-Assisted Laser Desorption/Ionisation Time-of-Flight mass spectrometry (MALDI-TOF MS) or Electrospray Ionisation mass spectrometry (ESI MS). Among the urinary proteins separated by SDS PAGE, 2-DE and OFFGEL respectively, exclusive autoreactivity was identified in PCa sera to …
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ANALYSIS OF PHARMACEUTICALS AND BIOMOLECULES USING HPLC COUPLED TO ICP-MS AND ESI-MS
… acids to facilitate determination by HPLC-electrospray ionisation tandem mass spectrometry (ESIMS/ MS) in positive ion mode. Improvements in detection limits post-derivatisation were achieved, and this method was successfully used for the determination of sorbic acid in a sample of …
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